PIWL2_MOUSE Q8CDG1
We list detailed information on various proteins on this webpage, which EnkiLife references when developing protein-related products. The protein data is sourced from UniProt, and since UniProt updates its information periodically, the data on our webpage may not always be up-to-date or may contain inaccuracies. If you notice any errors while browsing, we warmly welcome your feedback. Additionally, if you have any suggestions regarding any aspect of our website, please feel free to share them with us. As a token of our appreciation, we will offer a free product or a discount voucher for purchases to scientists who provide feedback. Please contact us at Email: order@enkilife.com; to share your feedback and get your rewards.
UniProt:Q8CDG1
Recommended name：Piwi-like protein 2
EC number：EC 3.1.26.-
Alternative names：
Cleaved into：
GeneID：57746
Gene names (primary )：Piwil2
Gene names (synonym )：Mili
Gene names (ORF )：
Length：971
Mass：109488
Sequence：MDPVRPLFRGPTPVHPSQCVRMPGCWPQAPRPLEPAWGRAGPAGRGLVFRKPEDSSPPLQPVQKDSVGLVSMFRGMGLDTAFRPPSKREVPPLGRGVLGRGLSANMVRKDREEPRSSLPDPSVLAAGDSKLAEASVGWSRMLGRGSSEVSLLPLGRAASSIGRGMDKPPSAFGLTARDPPRLPQPPALSPTSLHSADPPPVLTMERKEKELLVKQGSKGTPQSLGLNLIKIQCHNEAVYQYHVTFSPSVECKSMRFGMLKDHQSVTGNVTAFDGSILYLPVKLQQVVELKSQRKTDDAEISIKIQLTKILEPCSDLCIPFYNVVFRRVMKLLDMKLVGRNFYDPTSAMVLQQHRLQIWPGYAASIRRTDGGLFLLADVSHKVIRNDSVLDVMHAIYQQNKEHFQDECSKLLVGSIVITRYNNRTYRIDDVDWNKTPKDSFVMSDGKEITFLEYYSKNYGITVKEDDQPLLIHRPSERQNNHGMLLKGEILLLPELSFMTGIPEKMKKDFRAMKDLTQQINLSPKQHHGALECLLQRISQNETASNELTRWGLSLHKDVHKIEGRLLPMERINLRNTSFVTSEDLNWVKEVTRDASILTIPMHFWALFYPKRAMDQARELVNMLEKIAGPIGMRISPPAWVELKDDRIETYIRTIQSLLGVEGKIQMVVCIIMGTRDDLYGAIKKLCCVQSPVPSQVINVRTIGQPTRLRSVAQKILLQMNCKLGGELWGVDIPLKQLMVIGMDVYHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKYYEVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQKCFEAFDNYHPKMVVFVVQKKISTNLYLAAPDHFVTPSPGTVVDHTITSCEWVDFYLLAHHVRQGCGIPTHYICVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAHKLAFLSGQILHHEPAIQLCGNLFFL
Tissue specificity：Expressed in adult testis, specifically in spermatocytes and in spermatogonia (PubMed:11279525, PubMed:11578866, PubMed:12906857, PubMed:18404146, PubMed:18922463, PubMed:19114715, PubMed:19377467, PubMed:28903391). Only detected in primordial germ cells of both sexes. Widely expressed in tumors. Also present at early stages of oocyte growth. Present in the mitotic spermatogonia (PubMed:23706823). Not detected in the first stages of meiosis (preleptotene and leptotene) (PubMed:23706823). Detected at the late zygotene stage and increases throughout pachytene, declining from this stage onward until expression stops at the early round spermatid stage (at protein level) (PubMed:23706823). {ECO:0000269|PubMed:11279525, ECO:0000269|PubMed:11578866, ECO:0000269|PubMed:12906857, ECO:0000269|PubMed:18404146, ECO:0000269|PubMed:18922463, ECO:0000269|PubMed:19114715, ECO:0000269|PubMed:19377467, ECO:0000269|PubMed:23706823, ECO:0000269|PubMed:28903391}.
Induction：
Developmental stage：Expressed from 12.5 dpc until adult in male gonads. In female gonads, detected since 12.5 dpc, then begins to cease after birth and disappears until the development of adult ovary. {ECO:0000269|PubMed:11578866}.
Protein families：Argonaute family, Piwi subfamily