ASIC3_MOUSE Q6X1Y6
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UniProt:Q6X1Y6
Recommended name:Acid-sensing ion channel 3
EC number:
Alternative names:(ASIC3) (Amiloride-sensitive cation channel 3) (Dorsal root ASIC) (DRASIC)
Cleaved into:
GeneID:171209
Gene names (primary ):Asic3
Gene names (synonym ):Accn3 Drasic
Gene names (ORF ):
Length:530
Mass:58704
Sequence:MKPPSGLEEAQRRQASDIRVFANSCTMHGLGHIFGPGGLTLRRGLWATAVLLSLAAFLYQVAERVRYYGEFHHKTTLDERESHQLTFPAVTLCNINPLRRSRLTPNDLHWAGTALLGLDPAEHAAYLRALGQPPAPPGFMPSPTFDMAQLYARAGHSLEDMLLDCRYRGQPCGPENFTVIFTRMGQCYTFNSGAQGAELLTTPKGGAGNGLEIMLDVQQEEYLPIWKDMEETPFEVGIRVQIHGQEEPPAIDQLGFGAAPGHQTFVSCQQQQLSFLPPPWGDCNTASVDPDFDPEPSDPLGSPSSSPPYSLIGCRLACESRYVARKCGCRMMHMPGNSPVCSPQQYKDCASPALDAMLRKDTCVCPNPCATTRYAKELSMVRIPSRASARYLARKYNRSETYITENVLVLDIFFEALNYEAVEQKAAYEVSELLGDIGGQMGLFIGASLLTILEILDYLCEVFQDRVLGYFWNRRSSQRRSGNTLLQEELNGHRTHVPHLSLGPRPPTAPSAVTKTLAASHRTCYLVTRL
Tissue specificity:Expressed in liver, lung, kidney, testis, brain, eye and cochlea. Expressed in spiral ganglion and sensory hair cells of the organ of Corti in the cochlea (at protein level). Expressed in dorsal root ganglion innervating muscles and spinal chord. Expressed in peripheral sensory nerve termimals like nerves of the Meissner corpuscle, palisades of lanceolate nerve endings, site of mechanoreception in guard hair follicles, and Merkel cell-neurite complexes. {ECO:0000269|PubMed:11754838, ECO:0000269|PubMed:14659506, ECO:0000269|PubMed:15051137}.
Induction:
Developmental stage:
Protein families:Amiloride-sensitive sodium channel (TC 1.A.6) family, ASIC3 subfamily