NANO2_MOUSE P60322
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UniProt:P60322
Recommended name:Nanos homolog 2
EC number:
Alternative names:(NOS-2)
Cleaved into:
GeneID:378430
Gene names (primary ):Nanos2
Gene names (synonym ):Nos2
Gene names (ORF ):
Length:136
Mass:15597
Sequence:MDLPPFDMWRDYFNLSQVVMDIIQSRKQRQEGEVAEEPNSRPQEKSEQDLEGYPGCLPTICNFCKHNGESRHVYTSHQLKTPEGVVVCPILRHYVCPLCGATGDQAHTLKYCPLNSSQQSLYRRSGRNSAGRRVKR
Tissue specificity:Predominantly expressed in male germ cells. Expressed in self-renewing spermatogonial stem cells and developing gonads. {ECO:0000269|PubMed:12947200, ECO:0000269|PubMed:19745153}.
Induction:
Developmental stage:First detectable at 13.5 dpc in the male gonocytes, levels increase until about 16.5 dpc and then slightly decrease by 17.5 dpc (at protein level). Expression is maintained in all male gonocytes during embryogenesis, but becomes confined to a small population of the spermatogonia after birth. {ECO:0000269|PubMed:17138666, ECO:0000269|PubMed:20133598}.
Protein families:Nanos family