NANO2_MOUSE   P60322


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UniProt:P60322

Recommended name:Nanos homolog 2

EC number:

Alternative names:(NOS-2)

Cleaved into:

GeneID:378430

Gene names  (primary ):Nanos2

Gene names  (synonym ):Nos2

Gene names  (ORF ):

Length:136

Mass:15597

Sequence:MDLPPFDMWRDYFNLSQVVMDIIQSRKQRQEGEVAEEPNSRPQEKSEQDLEGYPGCLPTICNFCKHNGESRHVYTSHQLKTPEGVVVCPILRHYVCPLCGATGDQAHTLKYCPLNSSQQSLYRRSGRNSAGRRVKR

Tissue specificity:Predominantly expressed in male germ cells. Expressed in self-renewing spermatogonial stem cells and developing gonads. {ECO:0000269|PubMed:12947200, ECO:0000269|PubMed:19745153}.

Induction:

Developmental stage:First detectable at 13.5 dpc in the male gonocytes, levels increase until about 16.5 dpc and then slightly decrease by 17.5 dpc (at protein level). Expression is maintained in all male gonocytes during embryogenesis, but becomes confined to a small population of the spermatogonia after birth. {ECO:0000269|PubMed:17138666, ECO:0000269|PubMed:20133598}.

Protein families:Nanos family


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