NPHP1_MOUSE Q9QY53
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UniProt：UniProta
Recommended name：Nephrocystin-1
EC number：
Alternative names：
Cleaved into：
geneID：53885
Gene names (primary )：Nphp1
Gene names (synonym )：Nph1
Gene names (ORF )：
Length：687
Mass：77035
Sequence：MLARRPRDPLQALRRRGQELKLQVDSLVTESQLTGALEPSKRREIYQRCIQLKQAVDENKNTLQKLNKADEAAPVGNYEQRKEEEHSLLEKLACQLQELAVSISRKDALKVEAHSDKEEDDTTEDDEEETGGEEEESEGDGEGKQEQASPKQAETETVTYIALGDFAAQQTGDLTFKKGDVLHIIEKKPDGWWLAKDAEGVEGLIPRTYLEPYNKEDKLESSEGSEEGGEEDGEEDVEVVDETADGAQVKQRTDSHWSAVRKAISEQINTVDVLATMGAIPAGFRPSTLSQLLDEAGNQFRASYFLQPELTTSQLAFRDLTWDAKAGTIMSRPSRVSLILTLWSCKMIPLPGTSIQVLSRHIRLCLFDGSKVLSNIHTVRAVWQPKKPKTWTFSPQVTGILPCLLDGDCFIRSNSSTPDLGILFELGISYIRNSTGERGELSCGWVFLKLFDASGVPIPAKTYELFLNGGTPYEKGVEVDPSVSRRAQGSVFRQMISVRRQPQLLVKLRSLNRRSRAMLSLLPETLVGSMCSAHLLIFYRQILGDVLLRDRTNLQSADLISHPVLATFPLLLEQPDVMDALRSSWSEKESTLKRAEKRDKELLKAEFLLVYHDCVLPLLHSTLLPPFRWAEEETEAARWKAIADFLKQSRENEGSLKALLSPDGVHKPFDLSEQTFDFLGEIRKNSG
Tissue specificity：Expressed in the retina (at protein level) (PubMed:16885411, PubMed:19208653, PubMed:29899041). Expressed in the testis (at protein level) (PubMed:10665934). Widespread expression, with weak expression in skeletal muscle, kidney, thyroid, ovary, lung, prostate, thymus, uterus, heart, and liver (PubMed:10665934). Lowest levels in brain and spleen (PubMed:10665934). {ECO:0000269|PubMed:10665934, ECO:0000269|PubMed:16885411, ECO:0000269|PubMed:19208653, ECO:0000269|PubMed:29899041}.
Induction：
Developmental stage：Widespread and uniform expression in whole embryo at all development stages (PubMed:10665934). Expressed in cell stages of the first meiotic division and thereafter (PubMed:10665934). Initially expressed at day 14 with consistent expression thereafter to day 365 (PubMed:18684731). {ECO:0000269|PubMed:10665934, ECO:0000269|PubMed:18684731}.
Protein families：Nephrocystin-1 family