PMGT2_MOUSE Q8BW41
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UniProt:Q8BW41
Recommended name:Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2
EC number:EC 2.4.1.312
Alternative names:(POMGnT2) (Extracellular O-linked N-acetylglucosamine transferase-like) (Glycosyltransferase-like domain-containing protein 2)
Cleaved into:
GeneID:215494
Gene names (primary ):Pomgnt2
Gene names (synonym ):Ago61 Eogtl Gtdc2
Gene names (ORF ):
Length:605
Mass:69378
Sequence:MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALGQQSLDPVLGLKIDYPKALQILMEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNSSVMLPNLGSRRFQPALLDLSTVEDHNAQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLRQFPGLAQEARLFFMEGWGEGAHFDLYKLLSPKQPLLRAQLKTLGRLLCFSHAFVGLSKVTTWYQYGFVQPQGPKANILVSGNEIRQFTRFMTERLNVSHAGAPLGEEYILVFSRTQNRLILNEAELLLELAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTALFLPRGATVVELFPYAVNPDHYTPYKTLATLPGMDLQYVAWRNMIRENTVTHPERPWDQGGITHLDRAEQARILQSREVPRHLCCRNPEWLFRIYQDTRVDIPSLMQSIRRVVKGRPGPRRQRWAISLYPGKVREARCQASVQGATEARLSVSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYMLTLQNHTFTENIKPFTTYLVWVRCIFNRSLLGPFCRCAGVQHVASRPWPGLWRAPLAGSAFPGPQFC
Tissue specificity:Mainly expressed in the central nervous system. {ECO:0000269|PubMed:24256719}.
Induction:
Developmental stage:Expressed during brain development. At 14.5 dpc, expressed throughout the cortical plate and the developing brain, as well as throughout the eye, including the lens and cornea. Cortical expression is already detected at 12.5 dpc, peaks between 14.5 and 16.5 dpc and is reduced at birth. {ECO:0000269|PubMed:22958903}.
Protein families:Glycosyltransferase 61 family