PMGT2_MOUSE   Q8BW41


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UniProt:Q8BW41

Recommended name:Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

EC number:EC 2.4.1.312

Alternative names:(POMGnT2) (Extracellular O-linked N-acetylglucosamine transferase-like) (Glycosyltransferase-like domain-containing protein 2)

Cleaved into:

GeneID:215494

Gene names  (primary ):Pomgnt2

Gene names  (synonym ):Ago61 Eogtl Gtdc2

Gene names  (ORF ):

Length:605

Mass:69378

Sequence:MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALGQQSLDPVLGLKIDYPKALQILMEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNSSVMLPNLGSRRFQPALLDLSTVEDHNAQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLRQFPGLAQEARLFFMEGWGEGAHFDLYKLLSPKQPLLRAQLKTLGRLLCFSHAFVGLSKVTTWYQYGFVQPQGPKANILVSGNEIRQFTRFMTERLNVSHAGAPLGEEYILVFSRTQNRLILNEAELLLELAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTALFLPRGATVVELFPYAVNPDHYTPYKTLATLPGMDLQYVAWRNMIRENTVTHPERPWDQGGITHLDRAEQARILQSREVPRHLCCRNPEWLFRIYQDTRVDIPSLMQSIRRVVKGRPGPRRQRWAISLYPGKVREARCQASVQGATEARLSVSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYMLTLQNHTFTENIKPFTTYLVWVRCIFNRSLLGPFCRCAGVQHVASRPWPGLWRAPLAGSAFPGPQFC

Tissue specificity:Mainly expressed in the central nervous system. {ECO:0000269|PubMed:24256719}.

Induction:

Developmental stage:Expressed during brain development. At 14.5 dpc, expressed throughout the cortical plate and the developing brain, as well as throughout the eye, including the lens and cornea. Cortical expression is already detected at 12.5 dpc, peaks between 14.5 and 16.5 dpc and is reduced at birth. {ECO:0000269|PubMed:22958903}.

Protein families:Glycosyltransferase 61 family


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