BMP8B_MOUSE P55105
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UniProt:P55105
Recommended name：Bone morphogenetic protein 8B
EC number：
Alternative names：(BMP-8B)
Cleaved into：
GeneID：12164
Gene names (primary )：Bmp8b
Gene names (synonym )：
Gene names (ORF )：
Length：399
Mass：44943
Sequence：MAARPGLLWLLGLALCVLGGGHLSHPPHVFPQRRLGVREPRDMQREIREVLGLPGRPRSRAPVGAAQQPASAPLFMLDLYRAMTDDSGGGTPQPHLDRADLIMSFVNIVERDRTLGYQEPHWKEFHFDLTQIPAGEAVTAAEFRIYKEPSTHPLNTTLHISMFEVVQEHSNRESDLFFLDLQTLRSGDEGWLVLDITAASDRWLLNHHKDLGLRLYVETEDGHSIDPGLAGLLGRQAPRSRQPFMVGFFRANQSPVRAPRTARPLKKKQLNQINQLPHSNKHLGILDDGHGSHGREVCRRHELYVSFRDLGWLDSVIAPQGYSAYYCAGECIYPLNSCMNSTNHATMQALVHLMKPDIIPKVCCVPTELSAISLLYYDRNNNVILRRERNMVVQACGCH
Tissue specificity：Expressed in testis. Expressed in decidual cells of the uterus and in trophoblast cells of the labyrinthine region of the placenta and in the inner root sheath of hair follicles of early postnatal skin. Expressed in the extraembryonic ectoderm in pregastrula and gastrula stage mouse embryos. Expressed in brown adipose tissue and brain. {ECO:0000269|PubMed:10894154, ECO:0000269|PubMed:22579288}.
Induction：By feeding with high-fat diet and cold exposure. By beta-3-adrenergic receptor activation and thyroid hormone treatment. {ECO:0000269|PubMed:22579288}.
Developmental stage：Expressed during specific stages of spermatogenesis, with highest levels in stage 6-8 round spermatids after 3 weeks of age.
Protein families：TGF-beta family