COLI_MOUSE P01193
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UniProt:P01193
Recommended name：Pro-opiomelanocortin
EC number：
Alternative names：(POMC) (Corticotropin-lipotropin)
Cleaved into：NPP; Melanotropin gamma (Gamma-MSH); Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanocyte-stimulating hormone alpha (Alpha-MSH) (Melanotropin alpha); Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanocyte-stimulating hormone beta (Beta-MSH) (Melanotropin beta); Beta-endorphin; Met-enkephalin
GeneID：18976
Gene names (primary )：Pomc
Gene names (synonym )：Pomc1
Gene names (ORF )：
Length：235
Mass：26707
Sequence：MPRFCYSRSGALLLALLLQTSIDVWSWCLESSQCQDLTTESNLLACIRACKLDLSLETPVFPGNGDEQPLTENPRKYVMGHFRWDRFGPRNSSSAGSAAQRRAEEEAVWGDGSPEPSPREGKRSYSMEHFRWGKPVGKKRRPVKVYPNVAENESAEAFPLEFKRELEGERPLGLEQVLESDAEKDDGPYRVEHFRWSNPPKDKRYGGFMTSEKSQTPLVTLFKNAIIKNAHKKGQ
Tissue specificity：ACTH and MSH are produced by the pituitary gland.
Induction：[Beta-endorphin]: In hypothalamic paraventricular nucleus (PVN), up-regulated by cannabinoids, including the CNR1/CB1R agonist arachidonyl-29-chloroethylamide (ACEA) (at protein level). {ECO:0000269|PubMed:25707796}.
Developmental stage：
Protein families：POMC family