MOT12_MOUSE Q8BGC3
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UniProt:Q8BGC3
Recommended name:Monocarboxylate transporter 12
EC number:
Alternative names:(MCT 12) (Solute carrier family 16 member 12)
Cleaved into:
GeneID:240638
Gene names (primary ):Slc16a12
Gene names (synonym ):Mct12
Gene names (ORF ):
Length:486
Mass:53152
Sequence:MTKITRVSLASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYSQTAWIHSIVDCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGFILGSFATSLKHLYLSLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDRSVPEKNHNRESQREDCKQASPYSPLTKECTETRLCCSLQQEYGFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHHQAAFLMSILGVIDIVGNITFGWLTDRRCLKNYRYVCYLFAVALDGLCYLCLPMLQTFPLLVPFSCTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFAMIFSSILLGFVRIVKRMKRTQVPFPVKDSDPKLQLWTNGSVAYSVARELDQKDEEPLPKARSGCNLT
Tissue specificity:Expressed in eye lens. {ECO:0000269|PubMed:21778275}.
Induction:
Developmental stage:Expressed in lens at P1 and P7 (PubMed:21778275). The expression levels are higher than in adult lens (PubMed:21778275). Detected in the basolateral membrane of the lens epithelium, with strong staining at equatorial epithelium, and in differentiating secondary fiber cells at P1 (at protein level) (PubMed:21778275). {ECO:0000269|PubMed:21778275}.
Protein families:Major facilitator superfamily, Monocarboxylate porter (TC 2.A.1.13) family