SCNNA_MOUSE Q61180
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UniProt:Q61180
Recommended name:Amiloride-sensitive sodium channel subunit alpha
EC number:
Alternative names:(Alpha-NaCH) (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA)
Cleaved into:
GeneID:20276
Gene names (primary ):Scnn1a
Gene names (synonym ):
Gene names (ORF ):
Length:699
Mass:78893
Sequence:MLDHTRAPELNLDLDLDVSNSPKGSMKGNNFKEQDLCPPLPMQGLGKGDKREEQALGPEPSEPRQPTEEEEALIEFHRSYRELFQFFCNNTTIHGAIRLVCSKHNRMKTAFWAVLWLCTFGMMYWQFALLFEEYFSYPVSLNINLNSDKLVFPAVTVCTLNPYRYTEIKEDLEELDRITEQTLFDLYKYNSSYTRQAGGRRRSTRDLRGALPHPLQRLRTPPPPNPARSARSASSSVRDNNPQVDRKDWKIGFQLCNQNKSDCFYQTYSSGVDAVREWYRFHYINILSRLPDTSPALEEEALGSFIFTCRFNQAPCNQANYSQFHHPMYGNCYTFNNKNNSNLWMSSMPGVNNGLSLTLRTEQNDFIPLLSTVTGARVMVHGQDEPAFMDDGGFNVRPGVETSISMRKEALDSLGGNYGDCTENGSDVPVKNLYPSKYTQQVCIHSCFQENMIKKCGCAYIFYPKPKGVEFCDYLKQSSWGYCYYKLQAAFSLDSLGCFSKCRKPCSVTNYKLSAGYSRWPSVKSQDWIFEMLSLQNNYTINNKRNGVAKLNIFFKELNYKTNSESPSVTMVSLLSNLGSQWSLWFGSSVLSVVEMAELIFDLLVITLIMLLHRFRSRYWSPGRGARGAREVASTPASSFPSRFCPHPTSPPPSLPQQGTTPPLALTAPPPAYATLGPSASPLDSAVPGSSACAPAMAL
Tissue specificity:Expressed in kidney (at protein level) (PubMed:22207244). Expressed in lung (at protein level) (PubMed:22207244, PubMed:30659401). Expressed in the epididymis (at protein level) (PubMed:30659401). In the caput and corpus regions of the epididymis, expressed uniformly on the luminal and basal surfaces of the ducts and in the sperm in the duct lumen (PubMed:30659401). Also expressed in distal colon and, at low levels, in liver (PubMed:10409305). {ECO:0000269|PubMed:10409305, ECO:0000269|PubMed:22207244, ECO:0000269|PubMed:30659401}.
Induction:
Developmental stage:
Protein families:Amiloride-sensitive sodium channel (TC 1.A.6) family, SCNN1A subfamily