SCNNA_MOUSE   Q61180


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UniProt:Q61180

Recommended name:Amiloride-sensitive sodium channel subunit alpha

EC number:

Alternative names:(Alpha-NaCH) (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA)

Cleaved into:

GeneID:20276

Gene names  (primary ):Scnn1a

Gene names  (synonym ):

Gene names  (ORF ):

Length:699

Mass:78893

Sequence:MLDHTRAPELNLDLDLDVSNSPKGSMKGNNFKEQDLCPPLPMQGLGKGDKREEQALGPEPSEPRQPTEEEEALIEFHRSYRELFQFFCNNTTIHGAIRLVCSKHNRMKTAFWAVLWLCTFGMMYWQFALLFEEYFSYPVSLNINLNSDKLVFPAVTVCTLNPYRYTEIKEDLEELDRITEQTLFDLYKYNSSYTRQAGGRRRSTRDLRGALPHPLQRLRTPPPPNPARSARSASSSVRDNNPQVDRKDWKIGFQLCNQNKSDCFYQTYSSGVDAVREWYRFHYINILSRLPDTSPALEEEALGSFIFTCRFNQAPCNQANYSQFHHPMYGNCYTFNNKNNSNLWMSSMPGVNNGLSLTLRTEQNDFIPLLSTVTGARVMVHGQDEPAFMDDGGFNVRPGVETSISMRKEALDSLGGNYGDCTENGSDVPVKNLYPSKYTQQVCIHSCFQENMIKKCGCAYIFYPKPKGVEFCDYLKQSSWGYCYYKLQAAFSLDSLGCFSKCRKPCSVTNYKLSAGYSRWPSVKSQDWIFEMLSLQNNYTINNKRNGVAKLNIFFKELNYKTNSESPSVTMVSLLSNLGSQWSLWFGSSVLSVVEMAELIFDLLVITLIMLLHRFRSRYWSPGRGARGAREVASTPASSFPSRFCPHPTSPPPSLPQQGTTPPLALTAPPPAYATLGPSASPLDSAVPGSSACAPAMAL

Tissue specificity:Expressed in kidney (at protein level) (PubMed:22207244). Expressed in lung (at protein level) (PubMed:22207244, PubMed:30659401). Expressed in the epididymis (at protein level) (PubMed:30659401). In the caput and corpus regions of the epididymis, expressed uniformly on the luminal and basal surfaces of the ducts and in the sperm in the duct lumen (PubMed:30659401). Also expressed in distal colon and, at low levels, in liver (PubMed:10409305). {ECO:0000269|PubMed:10409305, ECO:0000269|PubMed:22207244, ECO:0000269|PubMed:30659401}.

Induction:

Developmental stage:

Protein families:Amiloride-sensitive sodium channel (TC 1.A.6) family, SCNN1A subfamily


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