SQSTM_MOUSE Q64337
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UniProt:Q64337
Recommended name：Sequestosome-1
EC number：
Alternative names：(STONE14) (Ubiquitin-binding protein p62)
Cleaved into：
GeneID：18412
Gene names (primary )：Sqstm1
Gene names (synonym )：A170 STAP
Gene names (ORF )：
Length：442
Mass：48163
Sequence：MASFTVKAYLLGKEEATREIRRFSFCFSPEPEAEAQAAAGPGPCERLLSRVAVLFPTLRPGGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRREHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHREHSKLIFPNPFGHLSDSFSHSRWLRKLKHGHFGWPGWEMGPPGNWSPRPPRAGDGRPCPTAESASAPPEDPNVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPTTPESSSTGTEDKSNTQPSSCSSEVSKPDGAGEGPAQSLTEQMKKIALESVGQPEEQMESGNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL
Tissue specificity：Widely expressed. {ECO:0000269|PubMed:10458914}.
Induction：By diethylmaleate, paraquat, menadione, sodium arsenite and cadmium chloride, arsenite and arsenate. By MG132, MG115, lactacystin and proteasome inhibitor I (PSI). By serum starvation, okadaic acid and glucose oxidase. Also up-regulated by RANK-L (at protein level). By etoposide and trichostatin. By the parkinsonian mimetic 6-hydroxydopamine (6-OHDA). By TGF-beta. {ECO:0000269|PubMed:10458914, ECO:0000269|PubMed:11162503, ECO:0000269|PubMed:12745069, ECO:0000269|PubMed:14960283, ECO:0000269|PubMed:15890008, ECO:0000269|PubMed:8806656, ECO:0000269|PubMed:9125146}.
Developmental stage：
Protein families：