IL36A_MOUSE Q9JLA2
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UniProt:Q9JLA2
Recommended name:Interleukin-36 alpha
EC number:
Alternative names:(FIL1 epsilon) (Interleukin-1 epsilon) (IL-1 epsilon) (Interleukin-1 family member 6) (IL-1F6) (Interleukin-1 homolog 1) (IL-1H1)
Cleaved into:
GeneID:54448
Gene names (primary ):Il36a
Gene names (synonym ):Fil1e Il1e Il1f6 Il1h1
Gene names (ORF ):
Length:160
Mass:18015
Sequence:MNKEKELRAASPSLRHVQDLSSRVWILQNNILTAVPRKEQTVPVTITLLPCQYLDTLETNRGDPTYMGVQRPMSCLFCTKDGEQPVLQLGEGNIMEMYNKKEPVKASLFYHKKSGTTSTFESAAFPGWFIAVCSKGSCPLILTQELGEIFITDFEMIVVH
Tissue specificity:Highly expressed in embryonic tissue and in tissues containing epithelial cells. Elevated expression levels are detected in chronic kidney disease; expressed inepithelia from the distal convoluted tubules (DCTs) to the cortical collecting ducts (CCDs) in single nephrons (at protein level). {ECO:0000269|PubMed:11466363, ECO:0000269|PubMed:20101239}.
Induction:By IL-22 in normal and psoriasis-like skin. {ECO:0000269|PubMed:21881584}.
Developmental stage:
Protein families:IL-1 family