IFT46_MOUSE Q9DB07
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UniProt:Q9DB07
Recommended name:Intraflagellar transport protein 46 homolog
EC number:
Alternative names:
Cleaved into:
GeneID:76568
Gene names (primary ):Ift46
Gene names (synonym ):
Gene names (ORF ):
Length:301
Mass:34054
Sequence:MADNSSDEYEEDNKEKKKPSQLTPQQGFSENDDDDDDDSSETDSDDDDDDEEHGAPLEGAYDPADYEHLPVSAEIKELFEYISRYTPQLIDLDHKLKPFIPDFIPAVGDIDAFLKVPRPDGKPDHLGLLVLDEPSTKQSDPTVLSLWLTENSKQHNITQHMKVKSLEDAEKNPKAIDTWIESISELHRSKPPATVHYTRPMPDIDTLMQEWSPEFEELLGKVSLPTVEIDCSLAEYIDMICAILDIPFYKSRIQSLHLLFSLYSEFKNSQHFKALAEGKKVFTPPPNSASQAGDAETLTFI
Tissue specificity:Strongly expressed in ovary and testis, moderately expressed in kidney and brain, and weakly expressed in thymus, heart, lung, liver, spleen and muscle. Expressed in embryonic bone and cartilage, with high expression in non-hypertrophic chondrocytes and weaker expression in hypertrophic chondrocytes. {ECO:0000269|PubMed:17720815}.
Induction:By BMP2. {ECO:0000269|PubMed:17720815}.
Developmental stage:Expressed from 8 dpc throughout embryonic development, with levels increasing at 12.5 dpc and remaining constant thereafter. Up-regulated during chondrocyte maturation and skeletogenesis. {ECO:0000269|PubMed:17720815}.
Protein families:IFT46 family