LRFN4_MOUSE Q80XU8
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UniProt:Q80XU8
Recommended name:Leucine-rich repeat and fibronectin type-III domain-containing protein 4
EC number:
Alternative names:
Cleaved into:
GeneID:225875
Gene names (primary ):Lrfn4
Gene names (synonym ):Salm3
Gene names (ORF ):
Length:636
Mass:67252
Sequence:MAPPLLLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRLVELGSSSLRGPVNLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQVPWAGIGSMPALHTLNLDHNLIDALPPGVFAQLSQLSRLDLTSNRLATLAPDPLFSRGRDAEASPSPLVLSFSGNPLHCNCELLWLRRLARPDDLETCASPPTLAGRYFWAVPEGEFSCEPPLIARHTQRLWVLEGQRATLRCRALGDPVPTMHWVGPDDRLVGNSSRAWAFPNGTLEIGVTGAGDAGAYTCIATNPAGEATARVELRVLALPHGGNTSAEGGRPGPSDIAASARTAAEGEGTLESEPAVQVTEVTATSGLVSWGLGRPADPVWMFQIQYNSSEDETLIYRIVPASSHHFLLKHLVPGADYDLCLLALSPAAGPSDLTATRLLGCAHFSTLPATPLCHALQAHVLGGTLTVAVGGVLVAALLVFTVALLVRGRGAGNGRLPLKLSHVQSQTNGGTSPMPKSHPPRSPPPRPQRSCSLDLGDTGGCYGYARRLGGAWARRSHSVHGGLLGAGCRGVGGSAERLEESVV
Tissue specificity:Expressed in brain and testis. In the brain, weak, but broad expression in the cerebral cortex and diencephalic nuclei. Also detected in other parts of the central nervous system, including the olfactory bulb, pons, cerebellum, and medulla oblongata, as well as in the peripheral nervous system, such as the ganglia of cranial nerves and the dorsal root ganglion during gestation. {ECO:0000269|PubMed:16828986}.
Induction:
Developmental stage:Low expression from 4.5 dpc onwards. Expression increases at 10.5 dpc and decreases after 15.5 dpc. At 11.5 dpc, broadly expressed in the telencephalic and diencephalic vesicles. This pattern of expression continues until 17.5 dpc. {ECO:0000269|PubMed:16828986}.
Protein families:LRFN family