LRAT_MOUSE Q9JI60
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UniProt:Q9JI60
Recommended name:Lecithin retinol acyltransferase
EC number:EC 2.3.1.135
Alternative names:(Phosphatidylcholine--retinol O-acyltransferase) (Phosphatidylcholine-retinol-O-acyltransferase)
Cleaved into:
GeneID:79235
Gene names (primary ):Lrat
Gene names (synonym ):
Gene names (ORF ):
Length:231
Mass:25820
Sequence:MKNPMLEAASLLLEKLLLISNFKLFSVSVPGGGTGKNRPYEISSFVRGDVLEVSRTHFIHYGIYLGENRVAHLMPDILLALTNDKERTQKVVSNKRLLLGVICKVASIRVDTVEDFAYGADILVNHLDGTLKKKSLLNEEVARRAEQQLGLTPYSLLWNNCEHFVTYCRYGSRISPQAEKFYDTVKIIIRDQRSSLASAVLGLASIVYTGLASYMTLPAICIPFCLWMMSG
Tissue specificity:Hepatic stellate cells and endothelial cells (at protein level). {ECO:0000269|PubMed:18544127}.
Induction:LRAT activity is up-regulated by dietary vitamin A (By similarity). Under conditions of vitamin A depletion, LRAT expression in the liver is induced by retinoic acid. {ECO:0000250, ECO:0000269|PubMed:11108736}.
Developmental stage:
Protein families:H-rev107 family