S22A6_RAT O35956
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UniProt:O35956
Recommended name：Solute carrier family 22 member 6 By Similarity
EC number：
Alternative names：
Cleaved into：
GeneID：29509
Gene names (primary )：Slc22a6
Gene names (synonym )：Oat1
Gene names (ORF )：
Length：551
Mass：60,766
Sequence：MAFNDLLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPPHHCRPPANANLSKDGGLEAWLPLDKQGQPESCLRFTSPQWGPPFYNGTEANGTRVTEPCIDGWVYDNSTFPSTIVTEWNLVCSHRAFRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAYAPNYTVYCVFRLLSGMSLASIAINCMTLNVEWMPIHTRAYVGTLIGYVYSLGQFLLAGIAYAVPHWRHLQLVVSVPFFIAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEEGAKLSIEVLRTSLQKELTLSKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSMYLIQVIFGAVDLPAKFVCFLVINSMGRRPAQMASLLLAGICILVNGIIPKSHTIIRTSLAVLGKGCLASSFNCIFLYTGELYPTVIRQTGLGMGSTMARVGSIVSPLVSMTAEFYPSMPLFIFGAVPVVASAVTALLPETLGQPLPDTVQDLKSRSRGKQNQQQQEQQKQMMPLQASTQEKNGL
Tissue specificity：Highly expressed in kidney; in the particular segment of the proximal tubule (PubMed:9228014, PubMed:9374486). In kidney, found preferentially in the cortex and outer medulla and weakly in the inner medulla (PubMed:9228014). Expressed to a lower extent in brain (PubMed:9228014). 2 s
Induction：
Developmental stage：Down-regulated by PGE2 and in ischemic kidney. 2 s
Protein families：major facilitator (TC 2.A.1) superfamily