X3CL1_MOUSE O35188
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UniProt:O35188
Recommended name:Fractalkine
EC number:
Alternative names:(C-X3-C motif chemokine 1) (CX3C membrane-anchored chemokine) (Neurotactin) (Small-inducible cytokine D1)
Cleaved into:Processed fractalkine
GeneID:20312
Gene names (primary ):Cx3cl1
Gene names (synonym ):Cx3c Fkn Scyd1
Gene names (ORF ):
Length:395
Mass:42099
Sequence:MAPSPLAWLLRLAAFFHLCTLLPGQHLGMTKCEIMCDKMTSRIPVALLIRYQLNQESCGKRAIVLETTQHRRFCADPKEKWVQDAMKHLDHQAAALTKNGGKFEKRVDNVTPGITLATRGLSPSALTKPESATLEDLALELTTISQEARGTMGTSQEPPAAVTGSSLSTSEAQDAGLTAKPQSIGSFEAADISTTVWPSPAVYQSGSSSWAEEKATESPSTTAPSPQVSTTSPSTPEENVGSEGQPPWVQGQDLSPEKSLGSEEINPVHTDNFQERGPGNTVHPSVAPISSEETPSPELVASGSQAPKIEEPIHATADPQKLSVLITPVPDTQAATRRQAVGLLAFLGLLFCLGVAMFAYQSLQGCPRKMAGEMVEGLRYVPRSCGSNSYVLVPV
Tissue specificity:Highest levels in brain. Lower levels in kidney, heart and lung. Also found in skeletal muscle and testis. {ECO:0000269|PubMed:9177350, ECO:0000269|PubMed:9479488, ECO:0000269|PubMed:9845323}.
Induction:By 12-O-tetradecanoylphorbol-13-acetate (TPA) and lipopolysaccharides (LPS) in bone marrow stroma cells. {ECO:0000269|PubMed:9177350}.
Developmental stage:
Protein families:Intercrine delta family