X3CL1_MOUSE   O35188


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UniProt:O35188

Recommended name:Fractalkine

EC number:

Alternative names:(C-X3-C motif chemokine 1) (CX3C membrane-anchored chemokine) (Neurotactin) (Small-inducible cytokine D1)

Cleaved into:Processed fractalkine

GeneID:20312

Gene names  (primary ):Cx3cl1

Gene names  (synonym ):Cx3c Fkn Scyd1

Gene names  (ORF ):

Length:395

Mass:42099

Sequence:MAPSPLAWLLRLAAFFHLCTLLPGQHLGMTKCEIMCDKMTSRIPVALLIRYQLNQESCGKRAIVLETTQHRRFCADPKEKWVQDAMKHLDHQAAALTKNGGKFEKRVDNVTPGITLATRGLSPSALTKPESATLEDLALELTTISQEARGTMGTSQEPPAAVTGSSLSTSEAQDAGLTAKPQSIGSFEAADISTTVWPSPAVYQSGSSSWAEEKATESPSTTAPSPQVSTTSPSTPEENVGSEGQPPWVQGQDLSPEKSLGSEEINPVHTDNFQERGPGNTVHPSVAPISSEETPSPELVASGSQAPKIEEPIHATADPQKLSVLITPVPDTQAATRRQAVGLLAFLGLLFCLGVAMFAYQSLQGCPRKMAGEMVEGLRYVPRSCGSNSYVLVPV

Tissue specificity:Highest levels in brain. Lower levels in kidney, heart and lung. Also found in skeletal muscle and testis. {ECO:0000269|PubMed:9177350, ECO:0000269|PubMed:9479488, ECO:0000269|PubMed:9845323}.

Induction:By 12-O-tetradecanoylphorbol-13-acetate (TPA) and lipopolysaccharides (LPS) in bone marrow stroma cells. {ECO:0000269|PubMed:9177350}.

Developmental stage:

Protein families:Intercrine delta family


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