FCSD2_MOUSE   Q3USJ8


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UniProt:Q3USJ8

Recommended name:F-BAR and double SH3 domains protein 2

EC number:

Alternative names:(Protein nervous wreck 1) (NWK1) (SH3 multiple domains protein 3)

Cleaved into:

GeneID:207278

Gene names  (primary ):Fchsd2

Gene names  (synonym ):Kiaa0769 Sh3md3

Gene names  (ORF ):

Length:740

Mass:84282

Sequence:MQPPPRKVKVTQELRNIQGEQMTKLQAKHQAECDLLEDMRTFSQKKAAIEREYAQGIQKLASQYLKRDWPGIKTDDRNDYRSMYPVWKSFLEGTMQVAQSRINICENYKNFISEPARAVRSLKEQQLKRCVDQLTKIQTELQETVKDLVKGKKKYFETEQMAHAVREKADIEAKSKLSLFQSRISLQKASVKLKARRSECNTKATHARNDYLLTLAAANAHQDRYYQTDLVNIMKALDGNVYDHLKDYLIAFSRTELETCQAIQNTFQFLLENSSKVVRDYNLQLFLQENAVFHKPQPFQFQPCDSDTSRQLESETGTTEEHSLNKEARKWATRVAREHKNIVHQQRVLNELECHGVALSEQSRAELEQKIDEARESIRKAEIIKLKAEARLDLLKQIGVSVDTWLKSAMNQVMEELENERWARPPAVTSNGTLHSLNADAEREEGEEFEDNMDVFDDSSSSPSGTLRNYPLTCKVVYSYKASQPDELTIEEHEVLEVIEDGDMEDWVKARNKVGQVGYVPEKYLQFPTSNSLLSMLQSLAALDSRSHTSSNSTEAELVSGSLNGDASVCFVKALYDYEGQTDDELSFPEGAIIRILNKENQDDDGFWEGEFSGRIGVFPSVLVEELSASENGDTPWTREIQISPSPKPHTSLPPLPLYDQPPSSPYPSPDKRSSQFFPRSPSANENSLHAESPGFSQASRQTPDTSYGKLRPVRAAPPPPTQNHRRTTEKMEDVEITLV

Tissue specificity:Detected in inner ear vestibula and in stereocilia in cochlear hair cell bundles (at protein level). Ubiquitous. Detected in testis, liver, brain cortex, cerebellum, kidney, organ of Corti, utricle, spiral ganglion, tongue and eye. {ECO:0000269|PubMed:23437151}.

Induction:

Developmental stage:Detected in brain cortex at 15.5 dpc and in neonates, but levels decrease 16.5 days after birth and are very low in adult brain cortex (at protein level). {ECO:0000269|PubMed:26567222}.

Protein families:


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