FBX5_MOUSE   Q7TSG3


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UniProt:Q7TSG3

Recommended name:F-box only protein 5

EC number:

Alternative names:(Early mitotic inhibitor 1)

Cleaved into:

GeneID:67141

Gene names  (primary ):Fbxo5

Gene names  (synonym ):Emi1

Gene names  (ORF ):

Length:421

Mass:47508

Sequence:MSRRTCSDLRRPSSCPCRLGARTTVDGCKEESPVLSVTMKCFNCNPDLSELEVVKPEDSGIEASYSPVCLEPSCNDCVRNHERLSFIDSPIVGHDNKENQRVQNTLDSSNETEELEASRLYEDSGYSSFTQSDRDDGILILENFRNSPQARLLPSQSPDQHPNKTLLPVLHFERVVCSTLKKNGKRNPKVDREMLKEVIASGNFRLQNIIGKKMGLEHLDILAELSRRGFVHLLANILTKLSGMDLVNLSKVSRIWKKILENNKGAFQLYSKTMQRVIESSKLSLHATTRGYVVGRAALTCVQKSSTWAPPKKDVQIKSSSQRGQRVSTYSRHNEFVEVAKTLKNNESLKACVRCNFPAKYDHYLERAVCKRESCQFEYCTKCLCAYHNNKDCLNGKILKASCKVGPLPGTKKSKKNLQRL

Tissue specificity:Expressed in oocytes and granulosa cells (PubMed:15526037, PubMed:17190794). Expressed in proliferating cells compartments in hair follicle and skin epidermis, spermatogonia, and intestinal crypts (PubMed:17875940). {ECO:0000269|PubMed:15526037, ECO:0000269|PubMed:17190794, ECO:0000269|PubMed:17875940}.

Induction:

Developmental stage:Detected at the germinal vesicle (GV) stage. During maturation, decreases to barely detectable levels in meiosis I- and meiosis II-stage oocytes. {ECO:0000269|PubMed:17190794}.

Protein families:


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