WNT3_MOUSE P17553
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UniProt:P17553
Recommended name:Proto-oncogene Wnt-3
EC number:
Alternative names:(Proto-oncogene Int-4)
Cleaved into:
GeneID:22415
Gene names (primary ):Wnt3
Gene names (synonym ):Int-4 Wnt-3
Gene names (ORF ):
Length:355
Mass:39659
Sequence:MEPHLLGLLLGLLLSGTRVLAGYPIWWSLALGQQYTSLASQPLLCGSIPGLVPKQLRFCRNYIEIMPSVAEGVKLGIQECQHQFRGRRWNCTTIDDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTSTICGCDSHHKGPPGEGWKWGGCSEDADFGVLVSREFADARENRPDARSAMNKHNNEAGRTTILDHMHLKCKCHGLSGSCEVKTCWWAQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRAKYALFKPPTERDLVYYENSPNFCEPNPETGSFGTRDRTCNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCVFHWCCYVSCQECIRIYDVHTCK
Tissue specificity:Detected at low levels in adult brain (PubMed:2162045). Dorsal portion of the neural tube, dorsal ectoderm, the branchial arches, and the limb buds. {ECO:0000269|PubMed:2162045}.
Induction:
Developmental stage:Detected at 6.25 to 7.5 dpc in primitive streak, proximal epiblast, visceral endoderm and at the junction between the embryonic and extraembryonic ectoderm, with higher levels in the posterior region (PubMed:10431240, PubMed:19841259). Detected in the ectoderm at forelimb buds at 9.5 dpc (PubMed:12569130). Detected in all outgrowing limbs and in ectoderm flanking the limbs at least till 11.5 dpc (PubMed:12569130). Highly expressed in embryos at 11.5 and 12.5 dpc, with very low expression levels before and after this period (PubMed:2162045). {ECO:0000269|PubMed:10431240, ECO:0000269|PubMed:12569130, ECO:0000269|PubMed:19841259, ECO:0000269|PubMed:2162045}.
Protein families:Wnt family