RFOX3_MOUSE Q8BIF2
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UniProt:Q8BIF2
Recommended name：RNA binding protein fox-1 homolog 3
EC number：
Alternative names：(Fox-1 homolog C) (Hexaribonucleotide-binding protein 3) (Fox-3) (Neuronal nuclei antigen) (NeuN antigen)
Cleaved into：
GeneID：52897
Gene names (primary )：Rbfox3
Gene names (synonym )：D11Bwg0517e Hrnbp3
Gene names (ORF )：
Length：374
Mass：40610
Sequence：MAQPYPPAQYPPPPQNGIPAEYAPPPPHPTQDYSGQTPVPPEHGMTLYTPAQTHPEQPGTEASTQPIAGTQTVPQADEAAQTDNQQLHPSDPTEKQQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFETSSDADRAREKLNGTIVEGRKIEVNNATARVMTNKKPGNPYANGWKLNPVVGTVYGPEFYAVTSFPYPTTGTAVAYRGAHLRGRGRAVYNTFRAAPPPPPIPTYGAALEQTLVKMPVPWAGLAPCPLPPQQTPEPAYPTSPAFPPLSCPFASRVVYQDGFYGAEIYGGYAAYRYAQPAAATAAAYSDSYGRVYAAADPYHHTIGPTATYSIGTMASLCRGGYSRFTPY
Tissue specificity：Widely expressed in brain, including in cerebral cortex, hippocampus, thalamus, caudate/putamen, cerebellum, as well as in the spinal cord (at protein level). Not expressed in all neuronal cells within a region, in cerebellum, expression is absent in Purkinje cells (at protein level). Expressed in the retina in the ganglion cells and some cells in the inner nuclear layer, but absent from the photoreceptor cells and most cells in the inner nuclear layer (at protein level). {ECO:0000269|PubMed:1483388, ECO:0000269|PubMed:15605376, ECO:0000269|PubMed:19713214, ECO:0000269|PubMed:21747913}.
Induction：By retinoic acid. Expression is up-regulated in P19 cells during neural differentiation upon retinoic acid treatment (at the protein level). {ECO:0000269|PubMed:19713214, ECO:0000269|PubMed:21747913}.
Developmental stage：In the neural tube, expressed as early as 9.5 dpc and expression is confined to the nervous system. By 12.5 dpc, can be found in the developing ventral horns and is also detected in the developing dorsal horns as well as in the dorsal root ganglion. Not detected in the ventricular zone, roof plate, floor plate or marginal zone (developing white matter). It is expressed from embryonic stage to adulthood. {ECO:0000269|PubMed:1483388}.
Protein families：