FCER2 molecular target information overview
Overview of FCER2 molecular targets
CD23 is a 45kDa type II transmembrane glycoprotein. CD23 is a type II membrane protein expressed by B cells, monocytes, macrophages, eosinophils, platelets, and dendritic cells. CD23 mediates IgE-dependent cytotoxicity and phagocytosis of macrophages and eosinophils.
Human FCER2 Molecular Target Information
Molecular name: FCER2, Fc epsilon receptor II
Alias:
- BLAST-2
- C-type lectin domain family 4, member J
- C-type lectin domain family 4, member J
- CD23
- CD23 antigen
- CD23A
- CLEC4J
- Fc epsilon receptor II
- Fc fragment of IgE, low affinity II, receptor for (CD23)
- fc fragment of ige, low affinity ii, receptor for (cd23a)
- fc-epsilon-RII
- FCE2
- IGEBF
- immunoglobulin E-binding factor
- immunoglobulin epsilon-chain
- low affinity immunoglobulin epsilon Fc receptor
- lymphocyte IgE receptor
Gene sequence:NCBI_Gene: 2208
Protein sequence:UniProtKB: P06734
Human FCER2 target molecular function (prediction)
Predicted to enable integrin binding activity. Involved in positive regulation of killing of cells of other organism; positive regulation of nitric-oxide synthase activity; and positive regulation of nitric-oxide synthase biosynthetic process. Located in extracellular exosome.
Mouse Fcer2a molecular target information
Molecular name:Fcer2a, Fc receptor, IgE, low affinity II, alpha polypeptide
Alias:
- CD23
- Fc epsilon low affinity receptor (IgE)
- FC epsilon RII
- Fce2
- low-affinity IgE receptor
- Ly-42
- lymphocyte antigen 42
Gene sequence:NCBI_Gene: 14128
Protein sequence:
Mouse Fcer2a target molecular function (prediction)
Predicted to enable carbohydrate binding activity. Acts upstream of or within positive regulation of humoral immune response mediated by circulating immunoglobulin. Located in external side of plasma membrane. Orthologous to human FCER2 (Fc fragment of IgE receptor II).
Rat Fcer2 molecular target information
Molecular name: Fcer2, Fc epsilon receptor II
Alias:
- CD23
- Fc fragment of IgE, low affinity II, receptor for (CD23)
- Fc receptor alpha multiple ligand receptor
- Fc receptor alpha, multiple ligand receptor
- Fc receptor, IgE, low affinity II, alpha polypeptide
- Fcalpha muR
- Fcalpha RII
- Fcer2a
- low affinity immunoglobulin epsilon Fc receptor
- MGC93219
Gene sequence:NCBI_Gene: 171075
Protein sequence:
Rat Fcer2 target molecular function (prediction)
Predicted to enable carbohydrate binding activity. Predicted to be involved in positive regulation of killing of cells of other organism; positive regulation of nitric-oxide synthase activity; and positive regulation of nitric-oxide synthase biosynthetic process. Predicted to act upstream of or within positive regulation of humoral immune response mediated by circulating immunoglobulin. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Orthologous to human FCER2 (Fc fragment of IgE receptor II).