SPY2_MOUSE Q9QXV8
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UniProt:Q9QXV8
Recommended name:Protein sprouty homolog 2
EC number:
Alternative names:(Spry-2)
Cleaved into:
GeneID:24064
Gene names (primary ):Spry2
Gene names (synonym ):
Gene names (ORF ):
Length:315
Mass:34623
Sequence:MEARAQSGNGSQPLLQTAHDSGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPTVVPRPGLKPAPRPSTQHKHERLHGLPEHRQPPRLQPSQVHSSRAPLSRSISTVSSGSRSSTRTSTSSSSSEQRLLGPSFSHGPAAADGIIRVQPKSELKPGDVKPLSKDDLGLHAYRCEDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSNDDEDNCADNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCKNSNTVCCKVPTVPPRNFEKPT
Tissue specificity:In adult, highly expressed in brain, lung, heart and at lower levels in skeletal muscle and kidney. {ECO:0000269|PubMed:10074434}.
Induction:
Developmental stage:At 8.5 dpc, expressed in the primitive streak, rostral forebrain, cells lateral to the posterior hindbrain, anterior hindbrain and developing midbrain. At 9.5 dpc, continues to be expressed in the rostral forebrain and primitive streak, and is also detected in the branchial arches and the forelimb bud. At 10.5 dpc, expressed in the somites, frontonasal processes, tailbud, and hindlimb bud (PubMed:10498682). Highly expressed in lung epithelial cells, primarily in the distal airways at 12 dpc (PubMed:10074434). {ECO:0000269|PubMed:10074434, ECO:0000269|PubMed:10498682}.
Protein families:Sprouty family