IRAK1_MOUSE Q62406
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UniProt:Q62406
Recommended name：Interleukin-1 receptor-associated kinase 1
EC number：EC 2.7.11.1
Alternative names：(IRAK) (IRAK-1) (Pelle-like protein kinase) (mPLK)
Cleaved into：
GeneID：16179
Gene names (primary )：Irak1
Gene names (synonym )：Il1rak
Gene names (ORF )：
Length：710
Mass：77269
Sequence：MAGGPGPGEPVVPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFAALIVRDQTELRLCERSEQRTASVLWPWINRNARVADLVHILTHLQLLRARDIITAWHPPAPVVPPSTAAPRPSSISAGSEAGDWSPRKLQSSASTFLSPAFPGSQTHSESELLQVPLPVSLGPPLPSSAPSSTKSSPESPVSGLQRAHPSPFCWPFCEISQGTCNFSEELRIGEGGFGCVYRAVMRNTTYAVKRLKEEADLEWTMVKQSFLTEVEQLSRFRHPNIVDFAGYCAESGLYCLVYGFLPNGSLEDQLHLQTQACSPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLMPKLGDFGLARFSRFAGAKASQSSTVARTSTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVILETLAGQRAVRTQGAKTKYLKDLIEDEAEEAGVTLKSTQPTLWVGVATDAWAAPIAAQIYKKHLDSRPGPCPPQLGLALAQLACCCMHRRAKKRPPMTQVYKRLEGLQAGPPWELEVAGHGSPSPQENSYMSTTGSAQSGDEPWQPLVVTTRAPAQAAQQLQRSPNQPVESDESVPGLSATLHSWHLTPGSHPSPASFREASCTQGGTTRESSVRSSPGFQPTTMEGSPTGSSSLLSSEPPQIIINPARQKMVQKLALYEEGVLDSLQLLSSGFFPGLDLEPEKSQGPEESDEFQS
Tissue specificity：Highly expressed in liver, followed by kidney and skeletal muscle. {ECO:0000269|PubMed:8663605}.
Induction：
Developmental stage：Expressed from 11 dpc to 18 dpc. {ECO:0000269|PubMed:8663605}.
Protein families：Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily