HOT_MOUSE Q8R0N6
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UniProt:Q8R0N6
Recommended name：Hydroxyacid-oxoacid transhydrogenase, mitochondrial
EC number：EC 1.1.99.24
Alternative names：(HOT) (Alcohol dehydrogenase iron-containing protein 1) (ADHFe1)
Cleaved into：
GeneID：76187
Gene names (primary )：Adhfe1
Gene names (synonym )：
Gene names (ORF )：
Length：465
Mass：49937
Sequence：MAAAARARVTHLLRHLQSTACQCPTHSHTYSQAPGPSGKTADYAFEMAVSNIRYGAGVTKEVGMDLQNMGAKNVCLMTDKNLSQLPPVQIVMDSLSKNGISFQVYDDVRVEPTDGSFMDAIEFAKKGAFDAYVAVGGGSTMDTCKAANLYASSPHSEFLDYVNAPIGKGKPVTVPLKPLIAVPTTSGTGSETTGVAIFDYEHLKVKTGIASRAIKPTLGLVDPLHTLHMPCQVVANSGFDVLCHALESYTAIPYSMRSPCPSNPIQRPAYQGSNPISDIWAVHALQIVAKYLKRAVRNPDDLEARSKMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKTYKAKEYNVDHPLVPHGLSVVLTSPAVFTFTAQMFPERHLETAGILGANIRTARIQDAGLVLADALRKFLFDLNVDDGLAALGYSKDDIPSLVKGTLPQERVTKLAPRAQSEEDLSALFEASMKLY
Tissue specificity：Expressed in white and brown adipose tissues, liver, and kidney. Expression is differentiation-dependent during in vitro brown and white adipogenesis. {ECO:0000269|PubMed:17559793}.
Induction：Down-regulated of 40% in white adipose tissue of ob/ob obese mice. {ECO:0000269|PubMed:17559793}.
Developmental stage：
Protein families：Iron-containing alcohol dehydrogenase family, Hydroxyacid-oxoacid transhydrogenase subfamily