ZBP1_MOUSE Q9QY24
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UniProt:Q9QY24
Recommended name:Z-DNA-binding protein 1
EC number:
Alternative names:(DNA-dependent activator of IFN-regulatory factors) (DAI) (Tumor stroma and activated macrophage protein DLM-1)
Cleaved into:
GeneID:58203
Gene names (primary ):Zbp1
Gene names (synonym ):Dlm1
Gene names (ORF ):
Length:411
Mass:44331
Sequence:MAEAPVDLSTGDNLEQKILQVLSDDGGPVKIGQLVKKCQVPKKTLNQVLYRLKKEDRVSSPEPATWSIGGAASGDGAPAIPENSSAQPSLDERILRFLEANGPHRALHIAKALGMTTAKEVNPLLYSMRNKHLLSYDGQTWKIYHSRQEGQDIAHSGVTQESPAIICQHNPVNMICQQGANSHISIANSNAIQIGHGNVIVREKACGEPGPRTSHPLPLAWDASAQDMPPVAHGAQYIYMDKSLLQQVQLGHHNEMSLVGDAGKHPSYSFSDSPPEVSTTTADPGASFNMQTFEPGPHPEGDTVQTVHIKSCFLEDATIGNGNKMTIHLRSKGEVMESGDSEEPKKEDTGTSSEATPPRSCQHTPSDSMLPTSELRAMALGDSSPQTTEPVLREHEVQDIESSQDTGLSKQ
Tissue specificity:Expressed in lung, spleen and liver. Lower levels were seen in heart, kidney and testis. Expression is greatly up-regulated in tumor stromal cells and activated macrophages. {ECO:0000269|PubMed:10564822}.
Induction:Expression is activated by IRF1 (PubMed:29321274). Up-regulated following interferon treatment (PubMed:10564822, PubMed:29073079). By lipopolysaccharides (LPS) (PubMed:10564822). {ECO:0000269|PubMed:10564822, ECO:0000269|PubMed:29073079, ECO:0000269|PubMed:29321274}.
Developmental stage:
Protein families: