VTCN1_MOUSE   Q7TSP5


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UniProt:Q7TSP5

Recommended name:V-set domain containing T-cell activation inhibitor 1

EC number:

Alternative names:(B7 homolog 4) (B7-H4) (Immune costimulatory protein B7-H4) (Protein B7S1) (T cell costimulatory molecule B7x)

Cleaved into:

GeneID:242122

Gene names  (primary ):Vtcn1

Gene names  (synonym ):B7h4

Gene names  (ORF ):

Length:283

Mass:30875

Sequence:MASLGQIIFWSIINIIIILAGAIALIIGFGISGKHFITVTTFTSAGNIGEDGTLSCTFEPDIKLNGIVIQWLKEGIKGLVHEFKEGKDDLSQQHEMFRGRTAVFADQVVVGNASLRLKNVQLTDAGTYTCYIRTSKGKGNANLEYKTGAFSMPEINVDYNASSESLRCEAPRWFPQPTVAWASQVDQGANFSEVSNTSFELNSENVTMKVVSVLYNVTINNTYSCMIENDIAKATGDIKVTDSEVKRRSQLQLLNSGPSPCVFSSAFVAGWALLSLSCCLMLR

Tissue specificity:Expressed on the surface of professional antigen-presenting cells (at protein level). Widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. {ECO:0000269|PubMed:12818165, ECO:0000269|PubMed:12818166, ECO:0000269|PubMed:12920180}.

Induction:Down-regulated upon activation of B-cells. {ECO:0000269|PubMed:12818166}.

Developmental stage:

Protein families:Immunoglobulin superfamily, BTN/MOG family


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