KLH40_MOUSE Q9D783
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UniProt:Q9D783
Recommended name：Kelch-like protein 40
EC number：
Alternative names：(Kelch repeat and BTB domain-containing protein 5)
Cleaved into：
GeneID：72330
Gene names (primary )：Klhl40
Gene names (synonym )：Kbtbd5
Gene names (ORF )：
Length：621
Mass：69589
Sequence：MTLGLEQAEEQRLYQQTLLQDGLKDMLDHGKFLDCVVRVGEREFPCHRLVLAACSPYFRARFLAEPDSAGEVRLEEVSPDVVSQVLHYLYTSEIALDEASVQDLFAAAHRFQIPSIFTICVSFLQKRLCLANCLAVFRLGLLLDCARLAVAARDFICARFPLVARDNDFLGLSADELIAIISSDGLNVEKEEAVFEAVMRWASSGDAEAQAERQRALPTVFESVRCRLLPRAFLETRVERHPLVRSQPELLRKVQMVKDAHEGRLTTLRKKKKEKGEQTARAKEANQGTEDTKAEDDEERVLPGILNDTLRFGMFLQDLIFMISEEGAVAYDPAANECYCASLSTQIPKNHVSLVTKENQVFVAGGLFYNEDNKEDPMSAYFLQFDHLDSEWLGMPPLPSPRCLFGLGEALNAIYVVGGRELKDSEDSLDSVLCYDRLSFKWGESDPLPYAVYGHTVLSHMDLVYVIGGKGKDRKCLNKMCVYDPKKFEWKELAPMQTARSLFGATVHDGRIFVAAGVTDTGLTSSSEVYSIADNKWTSFEAFPQERSSLSLVSLAGTLYALGGFATLETESGELVPTELNDIWRYNEDEKKWEGVLREIAYAAGATFLPVRLNVVRLTKM
Tissue specificity：Specifically expressed in skeletal muscles in embryonic, neonatal and adults (PubMed:24960163, PubMed:25940086). Expressed in various types of muscles, including extensor digitorum longus, gastrocnemius, soleus, diaphragm, masseter and heart (at protein level). Not detected in brain, liver and lung (at protein level). {ECO:0000269|PubMed:23746549, ECO:0000269|PubMed:24960163, ECO:0000269|PubMed:25940086}.
Induction：Up-regulated during myogenic differentiation (PubMed:24361185). Induced during the differentiation of myoblasts into myotubes (PubMed:23746549). {ECO:0000269|PubMed:23746549, ECO:0000269|PubMed:24361185}.
Developmental stage：Absent early during embryogenesis (7 dpc), present at the middle stage (11 dpc) and highly expressed at the later stages (15 dpc and 17 dpc) (PubMed:24361185). Specifically expressed in the somites at 11.5 dpc and in the skeletal muscle at 15.5 dpc (PubMed:24361185). {ECO:0000269|PubMed:24361185}.
Protein families：KLHL40 family