DEFI8_MOUSE   Q99J78


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UniProt:Q99J78

Recommended name:Differentially expressed in FDCP 8

EC number:

Alternative names:(DEF-8)

Cleaved into:

GeneID:23854

Gene names  (primary ):Def8

Gene names  (synonym ):D8Ertd713e

Gene names  (ORF ):

Length:448

Mass:52311

Sequence:MEYDEKLVRFRQAHLNPFNKQLGPRHHEQEPSEKVTSEDTLPELPAGEPEFHYSERMMDLGLSEDHFSRPVGLFLASDVQQLRQAIEECKQVILELPEQSEKQKDAVVRLIHLRLKLQELKDPNEEEPNIRVLLEHRFYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTGCCYRCHSKCLNLISKPCVSSKVSHQAEYELNICPETGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHCHWNDLAVIPARVVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINPLLFNYVEELVEIRKLRQDILLMKPYFITCKEAMEARLLLQLQDRQHFVENDEMYSIQDLLEVHMGRLSCSLTEIHTLFAKHIKLDCERCQAKGFVCELCKEGDVLFPFDSHTSVCNDCSAVFHRDCYYDNSTTCPKCARLTLRKQSLFQEPGLDMDA

Tissue specificity:Abundantly expressed in peripheral blood leukocytes. Highly expressed in B-cells. Also present in lymph node and appendix. Down-regulated upon macrophage/granulocyte differentiation. Weakly expressed in bone marrow and spleen. Weakly or not expressed in thymus and fetal liver. {ECO:0000269|PubMed:10460589}.

Induction:

Developmental stage:Abundantly expressed during embryogenesis. {ECO:0000269|PubMed:10460589}.

Protein families:DEF8 family


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