DEFI8_MOUSE Q99J78
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UniProt:Q99J78
Recommended name:Differentially expressed in FDCP 8
EC number:
Alternative names:(DEF-8)
Cleaved into:
GeneID:23854
Gene names (primary ):Def8
Gene names (synonym ):D8Ertd713e
Gene names (ORF ):
Length:448
Mass:52311
Sequence:MEYDEKLVRFRQAHLNPFNKQLGPRHHEQEPSEKVTSEDTLPELPAGEPEFHYSERMMDLGLSEDHFSRPVGLFLASDVQQLRQAIEECKQVILELPEQSEKQKDAVVRLIHLRLKLQELKDPNEEEPNIRVLLEHRFYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTGCCYRCHSKCLNLISKPCVSSKVSHQAEYELNICPETGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHCHWNDLAVIPARVVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINPLLFNYVEELVEIRKLRQDILLMKPYFITCKEAMEARLLLQLQDRQHFVENDEMYSIQDLLEVHMGRLSCSLTEIHTLFAKHIKLDCERCQAKGFVCELCKEGDVLFPFDSHTSVCNDCSAVFHRDCYYDNSTTCPKCARLTLRKQSLFQEPGLDMDA
Tissue specificity:Abundantly expressed in peripheral blood leukocytes. Highly expressed in B-cells. Also present in lymph node and appendix. Down-regulated upon macrophage/granulocyte differentiation. Weakly expressed in bone marrow and spleen. Weakly or not expressed in thymus and fetal liver. {ECO:0000269|PubMed:10460589}.
Induction:
Developmental stage:Abundantly expressed during embryogenesis. {ECO:0000269|PubMed:10460589}.
Protein families:DEF8 family