c-Fos proto-oncoprotein defines a family of closely related transcription factors (Fos proteins) also comprising Fra-1, Fra-2, FosB and ΔFosB, the latter two proteins being generated by alternative splicing. Through the regulation of many genes, most of them still unidentified, they regulate major functions from the cell level up to the whole organism. Thus they are involved in the control of proliferation, differentiation and apoptosis, as well as in the control of responses to stresses, and they play important roles in organogenesis, immune responses and control of cognitive functions, among others.
Product List
| Target | Catalog# | Product Name | Reactivity | Application |
|---|---|---|---|---|
c-Fos (8R6) | c-Fos (8R6) Rabbit Monoclonal Antibody | Human,Mouse,Rat | WB,IHC-P,ICC/IF,FC,IP,IF-P |
Related Products
Super-sensitive ECL chemiluminescent reagent
References
- Fos family protein degradation by the proteasome. Gomard T, et al. Biochem Soc Trans. 2008. [PMID: 18793151]
- The FOS transcription factor family differentially controls trophoblast migration and invasion. Renaud SJ, et al. J Biol Chem. 2014. [PMID: 24379408]
- The Fos family of transcription factors and their role in tumourigenesis. Milde-Langosch K. Eur J Cancer. 2005. [PMID: 16199154]
