XIRP2_MOUSE Q4U4S6
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UniProt:Q4U4S6
Recommended name：Xin actin-binding repeat-containing protein 2
EC number：
Alternative names：(Beta-xin) (Cardiomyopathy-associated protein 3) (Myogenic MEF2-activated Xin-related protein) (Myomaxin) (mXinbeta)
Cleaved into：
GeneID：241431
Gene names (primary )：Xirp2
Gene names (synonym )：Cmya3 Xin2
Gene names (ORF )：
Length：3784
Mass：428259
Sequence：MARYQAAVSRGDTRSFSANVMEESDVCTVPGGLAKMKRQFEKDKMTSTCNAFSEYQYRHESRAEQEAIHSSQEIIRRNEQEVSKGHGTDVFKAEMMSHLEKHTEETKQASQFHQYVQETVIDSPEEEELPKVSTKILKEQFEKSAQENFLRSDKETSPPAKCMKIENDIEETLKPSSAVGTSSSYTSTRQRKETSTSSYSNHSLTSTTLAQDNGTPSGKMEEFPPPPPDVCQTPMDVTAFSQSPEFPSPPRRLPMPKDLYSKQRNLYELNRLYRHIHPELRKNLEKDYISEVSEIVSSQINSGNALSADVQKARYVFENTNDSSQKDLNSERENLEWDEILKGEVQSIRWIFENQPLDSINHGSTDEGYTSKGIADQELIAGSDVKYTTWMFETQPIDALGIPSAGTEGNTEKIPELARGDVYTARWMFETRPLDSMNKMHECQEETASTLTKDITGGDVKTVRYMFETQQLDQLGQLHSVDELNLLQLRSELKEIKGNVKRSIKCFETQPLYVIRDGSGQMLEIKTVQREDIEKGDVRTARWMFETQPLDTINKDITEIKVVRGISMEENVKGGVSRAKWLFETQPLEKIKEESGEAVLKTEAVIGTDVSKKCWMFETQPLDILKDSPDTDSVSPEERIGGDVKTTKHLFETLPIEALKDSPDIGKLQKITASEEEKGDVKHQKWVFETQRLEDIREDKKEYTRTVRLEAVDRGHVKNYTHIFESNNLIKVDASHQIEVEGVTRGTVELNKSLFETTPLYAIQDHLGKYHQVKTVQQEEIVRGDVRSCRWLFETRPIDQFDESLHKFQIIRGISAQEIQAGNVKSARWLFETQPLDSIKYFSNVEETDSKTEQSTDIVKGDVKTCKWLFETQPMESLYEKASLMTNSEDIHKGDVRTCMWLFETQPLDAIKDDSEATVKLQTVKQEEIQGGDVQTACFLFETENLDNIQGDEGKENKPLEMDIQSGDVSGMKFKFENQSLDSINCSSENVLSKIKTLKAEDIQKGNVLKCRWLFENQPIDMIKESQECDGLVKTVTDVQGGDVRKGCFIFETFSLDEIKDESDGISMRETNLGEIIKGDVKSYKMLFETQPLYAIQDHEGFYHEVTTVKKEETIHGDVRGTRWLFETKPLDSIHESEDVYVIKSVTQEDIQKGDVSSVRYRFETQPLDMISDKSHNIVPTVDYIQGGNVQMNKQLFESEGGNKKNYVRTVSVNEIQKGNVKTSTWLFETHRIDELGEESRYENIKTVTQEDVQKGDVKQAVWLFENQTLDSINELDENDTKMTKEEIPPSDVKTTTWLFETTPIHEFNKTRVEKEEIIGKSIKETLEDLYSQRVVEAPGIIIEADEVGDVRMAKYKLMNQTTPEIQKEEVIRADLGNIMMNLLSQRDCTKKEIFVSEEEKGNVNFTKTQLLNRSMEFHAEKEEIVRGDVKQAIQKLFSEERRAKKGILIQEDEKGDINMTIYCLLHENAGDKTEREDILGGDVRRTIHNLLSSASNGKISERTKIDASERGNVQFFTTCIETGALDYLKQLQTGSNESTLTASKQEGEEEIIGGDVEGTKFLLKKRQSSFERTVSETDIIPGDVRHTVKVFMTEPQSSSYKTVKDEIIKGDLKSTLNSLNQAMNQKTVAKAEEIVKDDRLAILKSLKESGDRQKEPKQSGGMSRDIGQAIECLERATNTRTEILKKELILDDLKTSLRSLKEEQCGFKEVDKQGIVKDVLPGMLGFSERPKIGIHPAAVQRDKKSLLQPVPGPFEPAIKQQAGPGTLDETTQKPCLRSLIEERTEANLPKAPKGTVKIVIDREQNNDALEKSLRKMSNSEHRAMKNVLDMSDRMGIWTESKEYLCSDDHMSKHLSATMSIKESLKSKESENMREAKDDVISSTQSVDKTFRKQQTQTCELGNDQKSRFQDSYGKNQKNIQNIEITRDFQKQALLSQEKQYSNKEMKKNEASLQPLPVGKEVHSVPGVTVSGKNHKRIQATDKRQKTDVCLESQDFLMKTNTSKELKMAMERSFNPINLHPECGIKENEDSLPPPSPPPLPPSNASSEIEFPLPPPPPLMLLPGKNESPPSSPTEKTRTEFESLSTLPLPPPPVDEKAEQECLSTTLPPPPPPTPCQPGHLLPSSVLGHHREAFLQQFSQKEALGVHLPHSQAKILTGKSPPPTLPKPKLPKRIKDKMNQYSSSGELERSLSDVEIKATLSKDQKRSMVTMSSEHRETKQDVFGKGLVGRKQLPVDSANSLSQTVPEIPAPKEKQTAPLVKSHSFPSGSEQQSPKPYMRKFKTPLMIAEEKYRQQREELEKQRQESSSHNVIKTETQHQSLSEKEEEIELQKATEAISTPRKESDFPRARPNLDSESRAVIAGECSESQLATASTLTVATERLQHVLAASEDELTLRQEGIQNSSDASQSKLACETSQSHKECKAQQTFEQHVKRLPFPQTKPSSPSFKVKTIKLSTLDHTGTETDLSSKHHTKQSEVDIQTSTEQTDKEIKKTQASIQCDDKPSVPEKYFQLPKTEKRVTIQMPKEYAEKSHKSKLQTVPKKQGIFGEFDRGNVLGREGKNQDSSVSCSKEDRLIDERKQEHLQNQRVPRSVQQKVINERLDSQMQNFQQTEIQTSRSTIECEEFSQSYNATQEKTCLKDKGKQQGQVTSNTEESKQELRQNQSAFSSVKDSQHDDGKCTINILEFLRKREELQQILSRVKQFEAESSKSGLKTFQILLNIVPVWLISEEKREYGVRVAMENNFEKVKEEITHIKTQAEEMLLQCEHVIQTAMMASQTGKQRDKPTNLNEMPLNVSNVNLSSSKCTEQKESKTVEEKLTHRQVTTHPEAATRNPVKPYQEAKGEDGKMAPPSLKTRPPSPTFITIESTARRAETSTKSELSQSPKNNRCIEPPPRRPVEHASGLPRSRTPPSPPRSRSEQLVRLKDTTARLAKGTIPCSPGTPVPIVEKRSEVVMSPATLRRQIKIESRGGDSPPTITIPVSVNHVVSGSFRESVDAQEAVKKTEKTETYVHKDKMNSVNRAMPETESYDAVEIIRKVEGPHLSEHTERFEATNQTVQRAERFLNGHENEINRWFREFENDPVFRAKTERGAYANGEINHNMKQESHTFCKEEFGLASSETANFTGFSYRHPKVPAMQPRVHSEARSLNEHFSSVDAFDSQIVGSKVATSSSRSTEAGRSGFDFKHAPPTYEDVISGHILDVADSPTNLRRNFQKTWQESERVFQRVGYETSDAHATEMSRAFQEESAFLSDKEICIICQKTVYPMECLIADKQNFHKSCFRCHHCSSKLSLGNYASLHGRIYCKPHFKQLFKSKGNYDEGFGHKQHKDRWNCKNQSSLVDFIPSGEPDAHENPTADTLLLGDLTTHPDACNSKRQDNDLRKWGDRGKLKIVWPPCQEMPKKNSPPEEEFKVNKAKWPPEVTIPVPSDFKRESLTEHVKTLESQGQEQDSVPDLQPCKHVCQKEDITGIKEIKGYEERKDEKEAKDTLKDAEGLRSKRKSGMEFNDHNAHAQSDGKEKNALVNEADSADVLQVANTDDEGGPENHRENFNNNNNNSVAVSSLNNGRQKISISERPRLLQAVSEANYYTSEYQIKNFNNASKISELLGIFESQKLSSKKVLALALERTADRGTAGSPLQLVLEPGLQQGFSVKGENLAASPDVSPLHIKGNHENNKNVHLFFSNTVKITSFSKKHNILGCDLMDSVDQLKNMSCLYLRELGKNVKCWHGETAGAARHGGKMCFDAQSQGSAAKPVFPSMQCQAQHLTVEEQIKRDRCYSDSEAD
Tissue specificity：Expression is restricted to heart and skeletal muscle. Present in intercalated disks of the heart and in the Z-disk region of skeletal muscle (at protein level). {ECO:0000269|PubMed:17046827, ECO:0000269|PubMed:17766470}.
Induction：By MEF2A in skeletal muscle. By angiotensin II in heart. {ECO:0000269|PubMed:16500513, ECO:0000269|PubMed:17046827}.
Developmental stage：
Protein families：Xin family