GFI1B_MOUSE O70237
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UniProt:O70237
Recommended name:Zinc finger protein Gfi-1b
EC number:
Alternative names:(Growth factor independent protein 1B)
Cleaved into:
GeneID:14582
Gene names (primary ):Gfi1b
Gene names (synonym ):
Gene names (ORF ):
Length:330
Mass:37443
Sequence:MPRSFLVKSKKAHTYHQPRAQGDELVWPPAVIPVAKEHSQSASPLLSTPLPSQTLDWNTIKQEREMLLNQSLPKMASAPEGPLVTPQPQDGESPLSESPPFYKPSFSWDTLASSYSHSYTQTPSTMQSAFLERSVRLYGSPLVPSTESPLDFRLRYSPGMDTYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACDVCGKTFGHAVSLEQHTHVHSQERSFECRMCGKAFKRSSTLSTHLLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCTKGFQRKVDLRRHRESQHNLK
Tissue specificity:Expressed in bone marrow and in spleen. Detected in hematopoietic stem cells, erythroblasts, and megakaryocytes. Expressed in thymocytes. {ECO:0000269|PubMed:12351384, ECO:0000269|PubMed:12594258, ECO:0000269|PubMed:17095621, ECO:0000269|PubMed:9566867}.
Induction:Down-regulated by IL6 treatment in myelomonocytic cells, and in response to EPO in myeloid cells; EPO-induced down-regulation of Gfi1b is STAT5-dependent. {ECO:0000269|PubMed:11696536}.
Developmental stage:
Protein families: