RFX6_MOUSE Q8C7R7
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UniProt:Q8C7R7
Recommended name：DNA-binding protein RFX6
EC number：
Alternative names：(Regulatory factor X 6) (Regulatory factor X domain-containing protein 1)
Cleaved into：
GeneID：320995
Gene names (primary )：Rfx6
Gene names (synonym )：Rfxdc1
Gene names (ORF )：
Length：927
Mass：102566
Sequence：MAKVRELEEAFVQEQPSPQLPSEIAEECCAQLLGKGLLVYPEDSAYLLAETAAGARSSGEKGGDPGLQVGVKSEMQLNNGNFSSEEEDADTQESKTKAADPQLSQKKSITQMMKDKKKQTQLTLQWLEDNYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQHLVYQGCISKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHFWQGMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALIDKKIPILRRFVSSLKRQTSFLHLAQIARPALFDQHVVNAMVSDIEKVDLNSIGSQALLTISNSTDTESDIYSEHDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKMSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLANRNKASSLASDTVKNESHVETSYVPLPSSQPGAIPPALHPFSTEDTDNMPLPGQIELSQSTGHLMTPPISPAIASRGSVINQGPMASRPPSVGTVLSAPTHCSTYAEPIYPTLSPANHDFYGTNSNYQTMFRTQSHPASSLYAHRAEHGRCMAWTEQQLSRDFFGGSCAGSPYNCRPPSSYGPSTHTQESHSMQVLNTGSFNFLSNAGAGSCQGSTLPSNSPNGYYGNNINYSEAHRLGSMVNQHVSVISSVRSLPPYSDIHDPLNILDDSSRKQNNSFYADTLSPVACRTTVVASNLQTQIPSSSSQCMYGTSNQYPVQDSLDSNAASNREMVSSLPPINTVFMGTAAGDT
Tissue specificity：In the adult pancreas, expression is restricted to the islets where it could be detected in all endocrine lineages. {ECO:0000269|PubMed:20040487, ECO:0000269|PubMed:20148032}.
Induction：By Neurog3. {ECO:0000269|PubMed:20040487}.
Developmental stage：Expressed initially broadly in the definitive endoderm after gastrulation, becomes restricted to the gut and pancreatic bud at mid gestation, and is reactivated by Neurog3 in islet progenitor cells and is ultimately restricted to pancreatic islets in the mature pancreas (at protein level). {ECO:0000269|PubMed:20040487, ECO:0000269|PubMed:20148032}.
Protein families：RFX family