MLIP_MOUSE Q5FW52
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UniProt:Q5FW52
Recommended name:Muscular LMNA-interacting protein
EC number:
Alternative names:(Cardiac Isl1-interacting protein) (CIP) (Muscular-enriched A-type laminin-interacting protein)
Cleaved into:
GeneID:69642
Gene names (primary ):Mlip
Gene names (synonym ):Cip
Gene names (ORF ):
Length:269
Mass:29466
Sequence:MEFGKHEPGSSLKRNKNLEEGVTFEYSDHMTFSSESKQERVQRILDYPSEVSGRNSQQKEFNTKEPQGMQKGDLFKAEYVFIVDSDGEDEATCRQGEQGPPGGPGNIATRPKSLAISSSLASDVVRPKVRGADLKTSSHPEIPHGIAPQQKHGLALDEPARTESNSKASVLDLPVEHSSDSPSRPPQTMLGSETIKTPTTHPRAAGRETKYANLSSSSSTASESQLTKPGVIRPVPVKSKLLLRKDEEVYEPNPFSKYLEDNSGLFSEQ
Tissue specificity:Ubiquitous but more abundantly expressed in heart, skeletal and smooth muscle (at protein level). In brain, expressed by a subpopulation of cells within the hippocampus and cortex. In heart, expressed by ventricular cardiomyocytes. Expression is highly reduced in hypertrophic hearts (PubMed:26359501, PubMed:22343712, PubMed:26436652). {ECO:0000269|PubMed:21498514, ECO:0000269|PubMed:22343712, ECO:0000269|PubMed:26359501, ECO:0000269|PubMed:26436652}.
Induction:
Developmental stage:First detected in heart at 8.5 dpc and restricted to heart from 9.5 dpc to 15.5 dpc. At 9.5 dpc, transiently detected in the truck. From 11.5 dpc to 15.5 dpc, expression is higher in the ventricles of embryonic hearts. During embryogenesis, specifically expressed in cardiomyocytes. Myocardial expression continue in the adult heart. {ECO:0000269|PubMed:22343712}.
Protein families: