ACBG2_MOUSE   Q2XU92


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UniProt:Q2XU92

Recommended name:Long-chain-fatty-acid--CoA ligase ACSBG2

EC number:EC 6.2.1.3

Alternative names:(Acyl-CoA synthetase bubblegum family member 2) (Arachidonate--CoA ligase ACSBG2) (Bubblegum-related protein)

Cleaved into:

GeneID:328845

Gene names  (primary ):Acsbg2

Gene names  (synonym ):Bgr

Gene names  (ORF ):

Length:667

Mass:74319

Sequence:MTQEKKAEDLERGTDATSAVPRLWSTHCDGEVLLRLSKHGPGHETPMTIPELFQESAERFSAYPALASKNGKKWDTLTFSQYYEMCRKAAKSLIKLGLQRFQCVGILGFNSVEWVVTALGTILAGGLCVGIYATNSAEACQYVIQQANVSILIVENDQQLQKILLIPPDKMETVKAIVQYKLPLMESMANLYSWNDFMELGNDIPNIQLDRVILSQKANQCAVILYTSGTTGTPKGVLLSHDNITWTAGAMSQEMEINRVSGKQNTIVSYLPLSHIAAQLTDIWIPIKIGALTFFAQPDALRGTLVYTLQEVKPTLFMGVPRIWEKMQDTIKENVARSSRLRKKAFAWAKMLGLKVNTKRMLGKRDIPMNYRMAKALVFAKVRTSLGLDNCHAFFSSASPLSQDVSEFFLSLDIPIGEIYGMSECSGPHTVSNKSVYRVLSCGKVLSGCKNMLYNQNKEGVGEVCMWGRHVFMGYLNKEEATLEALDENGWLHSGDIGRLDSHDFLYITGRIKEILITAGGENVSPIPIETLVKEKIPIISHAMLVGDKAKFLCMLLTLKCETDRKSGEPLNKLSVEAKSFCQMLGSQATTVSDILKSRDQVVYTAIQYGIDIVNQQAMSDSHRIRKWIILEKDFSIQGGELGPTSKLKRSVITQKYKAQIDSMYLS

Tissue specificity:Testis- and brainstem-specific. Expressed in pubertal and adult testis. Enriched in germ cells and Sertoli cells while present at a lower level in Leydig cells. Present in testicular Sertoli cells and large motoneurons in the medulla oblongata and cervical spinal cord (at protein level). {ECO:0000269|PubMed:16371355, ECO:0000269|PubMed:16762313}.

Induction:

Developmental stage:

Protein families:ATP-dependent AMP-binding enzyme family, Bubblegum subfamily


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