THTM_MOUSE Q99J99
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UniProt:Q99J99
Recommended name:3-mercaptopyruvate sulfurtransferase
EC number:EC 2.8.1.2
Alternative names:(MST) (EC 2.8.1.2)
Cleaved into:
GeneID:246221
Gene names (primary ):Mpst
Gene names (synonym ):
Gene names (ORF ):
Length:297
Mass:33097
Sequence:MAAPQLFRALVSAQWVAEALKAPRSSQPLKLLDASWYLPKLGRDARREFEERHIPGAAFFDIDRCSDHTSPYDHMLPNATHFADYAGSLGVSAATHVVIYDDSDQGLYSAPRVWWMFRAFGHHSVSLLDGGFRHWLNQNLPISSGKSHSEPAEFSAQLDPSFIKTHEDILENLDARRFQVVDARAAGRFQGTQPEPRDGIEPGHIPGSVNIPFTEFLTNEGLEKSPEEIKRLFKEKKVDLSKPLVATCGSGVTACHVVLGAFLCGKSDVPVYDGSWVEWYMRAQPEHIISEGRGKTQ
Tissue specificity:Expressed in the brain and retina. In the retina, localized to the inner and outer plexiform layer, the inner and outer nuclear layer and the outer segments of photoreceptors. In the brain, localized to neurons of mitral cell layers, glomerular, and external plexiform layers in the olfactory bulb. Also found in Purkinje cell stomata and proximal dendrites. In the spinal cord, localized to large neurons. In the cerebral cortex, localized to pyramidial neurons in layers II/III and V, and in layers I-VI of neocortical areas. In the hippocampus, found in CA1 and CA3 pyramidal cells. {ECO:0000269|PubMed:18855522, ECO:0000269|PubMed:21937432, ECO:0000269|PubMed:22808324}.
Induction:
Developmental stage:In the developing brain, maintained expression from 16 dpc to postnatal day 14. Levels decrease between postnatal day 28 and postnatal day 52 and increase again with further aging up to 156 days old. {ECO:0000269|PubMed:18855522}.
Protein families: