CDYL_MOUSE Q9WTK2
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UniProt:Q9WTK2
Recommended name:Chromodomain Y-like protein
EC number:EC 4.2.1.-
Alternative names:(CDY-like) (Crotonyl-CoA hydratase) (Putative histone acetyltransferase Cdyl) (EC 2.3.1.48)
Cleaved into:
GeneID:12593
Gene names (primary ):Cdyl
Gene names (synonym ):
Gene names (ORF ):
Length:593
Mass:65211
Sequence:MGIGNSQPNSQEAQLCTLPEKAEQPTDDNTCQQNNVVPATVSEPDQASPAIQDAETQVESIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHNERQKEGSLARASRASPSNARKQISRSTHSTLSKTNSKALVVGKDHESKSSQLLAASQKFRKNPAPSLANRKNMDLAKSGIKILVPKSPVKGRTSVDGFQGESPEKLDPVDQGAEDTVAPEVTAEKPTGALLGPGAERARMGSRPRIHPLVPQVSGPVTAAMATGLAVNGKGTSPFMDALAANGTVTIQTSVTGVTAGKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMKEVQSALSTAAADDSKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMADAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLFSGRKLTAQEACGKGLVSQVFWPGTFTQEVMVRIKELASCNPVVLEESKALVRCNMKMELEQANERECEVLKKIWGSAQGMDSMLKYLQRKIDEF
Tissue specificity:Highly expressed in testis (at protein level) (PubMed:10192397). Expressed in the hippocampus (at protein level) (PubMed:28842554). Expressed in the medial prefrontal cortex, prelimbic cortex, intralimbic cortex and cingulate cortex area (at protein level) (PubMed:30665597). Isoform 1: Expressed as 2 transcripts encoding the same protein, a ubiquitous transcript and a highly expressed testis-specific transcript (PubMed:10192397). {ECO:0000269|PubMed:10192397, ECO:0000269|PubMed:28842554, ECO:0000269|PubMed:30665597}.
Induction:Down-regulated upon neuronal activity in the hippocampus (PubMed:28842554). Up-regulated after social defeat stress (PubMed:30665597). {ECO:0000269|PubMed:28842554, ECO:0000269|PubMed:30665597}.
Developmental stage:Highly expressed in elongating spermatids during histone hyperacetylation. {ECO:0000269|PubMed:12072557, ECO:0000269|PubMed:12947414}.
Protein families: