DACT2_MOUSE Q7TN08
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UniProt:Q7TN08
Recommended name:Dapper homolog 2
EC number:
Alternative names:(mDpr2) (Dapper antagonist of catenin 2)
Cleaved into:
GeneID:240025
Gene names (primary ):Dact2
Gene names (synonym ):Dpr2 Frd2
Gene names (ORF ):
Length:757
Mass:81668
Sequence:MWAPSGQGPAGWDRRRVGARLRAALAGLQELQGLRATQQARVRGALGLHPAPGPRGQELRLEAALTALREQLSRLRRQDAGLKTHLDQLDQQISELQLDVSRSSCEALDSDSRPSSGFYELSDAGSCSLSTSCASVCSDRLSPSLGSWLPVFQPSKSRSGIGDWRPRSADETTVPAWSPQLTEDSRLLHGAEGTGRLTGMFRPRPVSTGDLERVLPADVGLQRAGTDAAHLLGQGIEIPAHALDPTYQRDLVARGGQEVYPYPSPLHAVALQSPLFALPKEAPCFDICSPPQEPPLVPVDENRTQPEPIRELGSAEAYIHRLLHLRGQELPLRDVGQEQGGDTAAFPPKPCGQRSESTCQLEKQACGADRGGLKLGRGAAKDSLKQHGPVSLVGAEPLSSPLKEETIPWNPCVHGDNTVGSSPCSQAQQPLNDCGQGPVLSPSRVLGTESPPLAPEPFAYTSCTTGETSPVKLRMGFSQNKAVKVRRRVSEKVPRLGKQLPPQPERQRVTERDPSRPHQGGLSRRPTLAREPPGRSCSESTLYPVPFLVPVVVAQRESYPTSPQAFFPMEAALLSSAARRKQRRWQSTMEISAKAGSVSQPGPSMGLPRSPAKRGSGPRAQSRPTLARQDACARCESDPSEHSADCTSLYHSTIAETSEDEEASDHTANRFGDESSSNDSEGCFRGSRRRLAIGSAEAGQGGWAWPRVPPQQPSRAPGNTRPPLPPVPKLCRIKASKALKKKIRRFQPAALKVMTMV
Tissue specificity:Expressed in kidney (inner medullary collecting duct). Expressed in epidermal keratinocytes and hair follicles. {ECO:0000269|PubMed:18716284, ECO:0000269|PubMed:20685821}.
Induction:
Developmental stage:Expressed throughout the epiblast at the onset of gastrulation and in somites, the neural tube and gut at later stages of development. In the developing kidney is expressed in the ureteric bud/collecting duct epithelium. {ECO:0000269|PubMed:16881060, ECO:0000269|PubMed:17197390, ECO:0000269|PubMed:20685821}.
Protein families:Dapper family