GDF11_MOUSE Q9Z1W4
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UniProt:Q9Z1W4
Recommended name：Growth/differentiation factor 11
EC number：
Alternative names：(GDF-11) (Bone morphogenetic protein 11) (BMP-11)
Cleaved into：
GeneID：14561
Gene names (primary )：Gdf11
Gene names (synonym )：Bmp11
Gene names (ORF )：
Length：405
Mass：44947
Sequence：MVLAAPLLLGFLLLALELRPRGEAAEGPAAAAAAAAAAAGVGGERSSRPAPSAPPEPDGCPVCVWRQHSRELRLESIKSQILSKLRLKEAPNISREVVKQLLPKAPPLQQILDLHDFQGDALQPEDFLEEDEYHATTETVISMAQETDPAVQTDGSPLCCHFHFSPKVMFTKVLKAQLWVYLRPVPRPATVYLQILRLKPLTGEGTAGGGGGGRRHIRIRSLKIELHSRSGHWQSIDFKQVLHSWFRQPQSNWGIEINAFDPSGTDLAVTSLGPGAEGLHPFMELRVLENTKRSRRNLGLDCDEHSSESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGQCEYMFMQKYPHTHLVQQANPRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGCS
Tissue specificity：Highly expressed in the developing limb bud, initially detected in the distal mesenchyme, and later localizing to regions around the developing bones. Is also expressed in adult dental pulp and brain.
Induction：
Developmental stage：First strongly expressed in restricted domains at 8.5 dpc where it is highest in the tail bud. At 10.5 dpc, expressed in the branchial arches, limb bud, tail bud and posterior dorsal neural tube. Later, expressed in terminally-differentiated odontoblasts, the nasal epithelium, retina and specific regions of the brain. {ECO:0000269|PubMed:10075854, ECO:0000269|PubMed:10391213}.
Protein families：TGF-beta family