ANO5_MOUSE Q75UR0
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UniProt:Q75UR0
Recommended name:Anoctamin-5
EC number:
Alternative names:(Gnathodiaphyseal dysplasia 1 protein homolog) (Transmembrane protein 16E)
Cleaved into:
GeneID:233246
Gene names (primary ):Ano5
Gene names (synonym ):Gdd1 Tmem16e
Gene names (ORF ):
Length:904
Mass:106214
Sequence:MVEQEGLTAKEIDYAFQQNENLGSKETSFLIPEDLQSPPEKRFNLFLRRRLMFQRSEHSKDSVFFRDGIRQIDFVLSYVEDLKKDGELKAERRREFEQNLRKTGLDLETEDKLNSEDGKTYFVKIHAPWEVLVTYAEVLGIKMPIKLSDIPRPKYPPLSYMLGAVKLPSSVKYPTPEYFTAQFSRHRQELFLIEDEATFFPSSTRNRIVYYILSRCPFGVEEGKKKIGIERLLNSNTYLSAYPLHDGQYWKPSKTTRPNERYNLCKNWARFSYFYKEQPFHLIRNYFGEKIGIYFVFLGYYTEMLLFAALVGLACFIYGLLSMENNRTSTEICDPDIGGQMIMCPLCDEVCDYWRLNTTCLHSKFSHLFDNESTVFFALFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQQQLQLRPEFEAMCKHKKMNPVTKEMEPHMPLCHRIPWYFVSGTTVTFGMALLLSSMVSILIYRLSVFATFASFMESEATLQSVKSFFTPQLATALSGSCLNCIVILILNFFYEKISAWITKMEIPRTHQEYESSLTLKMFLFQFVNYYSSCFYVAFFKGKFVGYPGSYTYMFNIWRSEECGPAGCLIELTTQLTIIMIGKQIFGNIHEAFQPLIFNWWRRRRARTHSEKLYSRWEQDHDLQVYGHRGLFYEYLETVIQFGFATLFVASFPLAPLFALMNNIMGIRVDAWKLTTQYRRPVAAKAHSIGVWQDILFGMAIVSVATNAFIVSFTSDIIPRLVYFYAYSTNSTEPLSGYVNNSLSVFLIADFPNHTVPMEKKDFVTCRYRDYRYPPDHEDKYSHNMQFWHVLAAKMTFIIVMEHVVFLFKFLLAWLIPDVPKDVVEKIKREKLMTIKIIHDFELNKLKENLDVEYGNIMKNVLVDEDNSLKAKTTV
Tissue specificity:Highly expressed in skeletal muscle, bone tissues and thyroid gland. {ECO:0000269|PubMed:15124103, ECO:0000269|PubMed:15882990, ECO:0000269|PubMed:17418107, ECO:0000269|PubMed:20056604}.
Induction:Up-regulated during the course of myogenic differentiation. Down-regulated during osteoblastic differentiation. {ECO:0000269|PubMed:15124103, ECO:0000269|PubMed:15882990}.
Developmental stage:In the developing embryo, expressed mainly in differentiating and developing somites and is associated with myotomal somite lineages. {ECO:0000269|PubMed:17418107}.
Protein families:Anoctamin family