S19A2_MOUSE   Q9EQN9


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UniProt:Q9EQN9

Recommended name:Thiamine transporter 1

EC number:

Alternative names:(ThTr-1) (Solute carrier family 19 member 2)

Cleaved into:

GeneID:116914

Gene names  (primary ):Slc19a2

Gene names  (synonym ):

Gene names  (ORF ):

Length:498

Mass:55676

Sequence:MDVPARVSRRAAAAAARMLLRTARVPRECWFLPTALLCAYGFFANLRPSEPFLTPYLLGPDKNLTERQVYNEIYPVWTYSYLLLLFPVFLATDYLRYKPVILLQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYTVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILVSVVGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHIPSSCHGVNGLKVQNGGIVTDTPAANHLPGWEDIESKIPLNLDEPPVEEPEEPKPDRLRVFRVLWNDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYAQGLWEKVMPSQNADIYNGGVEAVSTLLGASAVFAVGYIKLSWSTWGEMTLFLCSLLIAAAVYVMDTVQSIWVCYASYVVFRIIYMVLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDARGLGLCITTQFLIYASYFAAISVVFLANGIVSIIKKCRKQEDPSSSPQASTS

Tissue specificity:Expressed in cochlear hair cells and duodenum (at protein level) (PubMed:11592824). Detected in pancreatic acinar cells (at protein level) (PubMed:22194418). Also expressed strongly in pancreatic islet cells (PubMed:22194418). Isoform 1: Very highly expressed in liver, and also detected at lower levels in heart, testis, kidney, brain and spleen (PubMed:11386850, PubMed:12031504). Isoform 2: Expressed at low levels in liver and spleen (PubMed:12031504). {ECO:0000269|PubMed:11386850, ECO:0000269|PubMed:11592824, ECO:0000269|PubMed:12031504, ECO:0000269|PubMed:22194418}.

Induction:

Developmental stage:At embryonic stage 16.5 dpc detected in intestinal enterocytes, pancreatic acinar cells, and cochlear hair cells (at protein level). In newborn mice, detected in brain, kidney, liver and intestine (at protein level). {ECO:0000269|PubMed:11592824}.

Protein families:Reduced folate carrier (RFC) transporter (TC 2.A.48) family


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