IKZF4_MOUSE   Q8C208


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UniProt:Q8C208

Recommended name:Zinc finger protein Eos

EC number:

Alternative names:(Ikaros family zinc finger protein 4)

Cleaved into:

GeneID:22781

Gene names  (primary ):Ikzf4

Gene names  (synonym ):Zfpn1a4

Gene names  (ORF ):

Length:586

Mass:64155

Sequence:MHTPPALPRRFQGGGRVRTPGSHRQGKDNLERELSGGCAPDFLPQAQDSNHFIMESLFCESSGDSSLEKEFLGAPVGPSVSTPNSQHSSPSRSLSANSIKVEMYSDEESSRLLGPDERLLDKDDSVIVEDSLSEPLGYCDGSGPEPHSPGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCNYCGRSYKQQSTLEEHKERCHNYLQSLSTDAQALTGQPGDEIRDLEMVPDSMLHPSTERPTFIDRLANSLTKRKRSTPQKFVGEKQMRFSLSDLPYDVNASGGYEKDVELVAHHGLEPGFGGSLAFVGTEHLRPLRLPPTNCISELTPVISSVYTQMQPIPSRLELPGSREAGEGPEDLGDGGPLLYRARGSLTDPGASPSNGCQDSTDTESNHEDRIGGVVSLPQGPPPQPPPTIVVGRHSPAYAKEDPKPQEGLLRGTPGPSKEVLRVVGESGEPVKAFKCEHCRILFLDHVMFTIHMGCHGFRDPFECNICGYHSQDRYEFSSHIVRGEHKVG

Tissue specificity:Expressed mainly in the brain. Up-regulated in long term cultured astrocytes. Down-regulated during osteoclast differentiation. {ECO:0000269|PubMed:10218586, ECO:0000269|PubMed:17403896}.

Induction:

Developmental stage:Highly expressed in the brain at 15 dpc and 18 dpc. Expression gradually decreased as postnatal development proceeded. No expression detected in the liver, kidney, lung, thymus or spleen during all developmental stages. {ECO:0000269|PubMed:10218586}.

Protein families:Ikaros C2H2-type zinc-finger protein family


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