IKZF4_MOUSE Q8C208
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UniProt:Q8C208
Recommended name:Zinc finger protein Eos
EC number:
Alternative names:(Ikaros family zinc finger protein 4)
Cleaved into:
GeneID:22781
Gene names (primary ):Ikzf4
Gene names (synonym ):Zfpn1a4
Gene names (ORF ):
Length:586
Mass:64155
Sequence:MHTPPALPRRFQGGGRVRTPGSHRQGKDNLERELSGGCAPDFLPQAQDSNHFIMESLFCESSGDSSLEKEFLGAPVGPSVSTPNSQHSSPSRSLSANSIKVEMYSDEESSRLLGPDERLLDKDDSVIVEDSLSEPLGYCDGSGPEPHSPGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCNYCGRSYKQQSTLEEHKERCHNYLQSLSTDAQALTGQPGDEIRDLEMVPDSMLHPSTERPTFIDRLANSLTKRKRSTPQKFVGEKQMRFSLSDLPYDVNASGGYEKDVELVAHHGLEPGFGGSLAFVGTEHLRPLRLPPTNCISELTPVISSVYTQMQPIPSRLELPGSREAGEGPEDLGDGGPLLYRARGSLTDPGASPSNGCQDSTDTESNHEDRIGGVVSLPQGPPPQPPPTIVVGRHSPAYAKEDPKPQEGLLRGTPGPSKEVLRVVGESGEPVKAFKCEHCRILFLDHVMFTIHMGCHGFRDPFECNICGYHSQDRYEFSSHIVRGEHKVG
Tissue specificity:Expressed mainly in the brain. Up-regulated in long term cultured astrocytes. Down-regulated during osteoclast differentiation. {ECO:0000269|PubMed:10218586, ECO:0000269|PubMed:17403896}.
Induction:
Developmental stage:Highly expressed in the brain at 15 dpc and 18 dpc. Expression gradually decreased as postnatal development proceeded. No expression detected in the liver, kidney, lung, thymus or spleen during all developmental stages. {ECO:0000269|PubMed:10218586}.
Protein families:Ikaros C2H2-type zinc-finger protein family