ANGL4_MOUSE Q9Z1P8
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UniProt:Q9Z1P8
Recommended name：Angiopoietin-related protein 4
EC number：
Alternative names：(425O18-1) (Angiopoietin-like protein 4) (Fasting-induced adipose factor) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP) (Secreted protein Bk89)
Cleaved into：ANGPTL4 N-terminal chain; ANGPTL4 C-terminal chain
GeneID：57875
Gene names (primary )：Angptl4
Gene names (synonym )：Farp Fiaf Ng27
Gene names (ORF )：
Length：410
Mass：45538
Sequence：MRCAPTAGAALVLCAATAGLLSAQGRPAQPEPPRFASWDEMNLLAHGLLQLGHGLREHVERTRGQLGALERRMAACGNACQGPKGKDAPFKDSEDRVPEGQTPETLQSLQTQLKAQNSKIQQLFQKVAQQQRYLSKQNLRIQNLQSQIDLLAPTHLDNGVDKTSRGKRLPKMTQLIGLTPNATHLHRPPRDCQELFQEGERHSGLFQIQPLGSPPFLVNCEMTSDGGWTVIQRRLNGSVDFNQSWEAYKDGFGDPQGEFWLGLEKMHSITGNRGSQLAVQLQDWDGNAKLLQFPIHLGGEDTAYSLQLTEPTANELGATNVSPNGLSLPFSTWDQDHDLRGDLNCAKSLSGGWWFGTCSHSNLNGQYFHSIPRQRQERKKGIFWKTWKGRYYPLQATTLLIQPMEATAAS
Tissue specificity：Detected in liver and kidney (PubMed:10698685, PubMed:17609370). Predominantly expressed in adipose tissue and is strongly up-regulated by fasting in white adipose tissue and liver. {ECO:0000269|PubMed:10698685, ECO:0000269|PubMed:10862772, ECO:0000269|PubMed:17609370}.
Induction：Induced in interstitial capillaries in response to hind leg ischemia (PubMed:17068295). Alterations in nutrition and leptin administration are found to modulate the expression in vivo. {ECO:0000269|PubMed:10866690, ECO:0000269|PubMed:17068295}.
Developmental stage：Detected in endothelial cells in the capillary plexus, veins and arteries in the retina at 2, 12 and 17 days after birth (PubMed:21832056). Expressed at low levels in most organs and connective tissue at 13.5 dpc. Between 15.5 dpc and 18.5 dpc, strongest expression in brown fat. {ECO:0000269|PubMed:10866690, ECO:0000269|PubMed:21832056}.
Protein families：