BMP8A_MOUSE P34821
We list detailed information on various proteins on this webpage, which EnkiLife references when developing protein-related products. The protein data is sourced from UniProt, and since UniProt updates its information periodically, the data on our webpage may not always be up-to-date or may contain inaccuracies. If you notice any errors while browsing, we warmly welcome your feedback. Additionally, if you have any suggestions regarding any aspect of our website, please feel free to share them with us. As a token of our appreciation, we will offer a free product or a discount voucher for purchases to scientists who provide feedback. Please contact us at Email: order@enkilife.com; to share your feedback and get your rewards.
UniProt:P34821
Recommended name：Bone morphogenetic protein 8A
EC number：
Alternative names：(BMP-8A) (Osteogenic protein 2) (OP-2)
Cleaved into：
GeneID：12163
Gene names (primary )：Bmp8a
Gene names (synonym )：Bmp-8 Bmp8
Gene names (ORF )：
Length：399
Mass：44764
Sequence：MAMRPGPLWLLGLALCALGGGHGPRPPHTCPQRRLGARERRDMQREILAVLGLPGRPRPRAQPAAARQPASAPLFMLDLYHAMTDDDDGGPPQAHLGRADLVMSFVNMVERDRTLGYQEPHWKEFHFDLTQIPAGEAVTAAEFRIYKEPSTHPLNTTLHISMFEVVQEHSNRESDLFFLDLQTLRSGDEGWLVLDITAASDRWLLNHHKDLGLRLYVETADGHSMDPGLAGLLGRQAPRSRQPFMVTFFRASQSPVRAPRAARPLKRRQPKKTNELPHPNKLPGIFDDGHGSRGREVCRRHELYVSFRDLGWLDWVIAPQGYSAYYCEGECAFPLDSCMNATNHAILQSLVHLMKPDVVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGCH
Tissue specificity：Expressed in testis. expressed in trophoblast cells of the labyrinthine region of the placenta and in the inner root sheath of hair follicles of early postnatal skin. {ECO:0000269|PubMed:8843393}.
Induction：By dexamethasone in calvarial osteoblasts. {ECO:0000269|PubMed:21277400}.
Developmental stage：Extensive expression found in 8-day embryos, fell drastically in 10-day embryos and virtually absent in 17-day embryos. Expressed during specific stages of spermatogenesis, with the highest levels in stage 6-8 round spermatids after 3 weeks of age. {ECO:0000269|PubMed:8843393}.
Protein families：TGF-beta family