INKA2_MOUSE Q80VY2
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UniProt:Q80VY2
Recommended name:PAK4-inhibitor INKA2
EC number:
Alternative names:(Induced in neural crest by AP2-alpha protein-related homolog) (MInca-r)
Cleaved into:
GeneID:109050
Gene names (primary ):Inka2
Gene names (synonym ):Fam212b
Gene names (ORF ):
Length:300
Mass:33233
Sequence:MTKESKDMDCYLRRLKQELMSMKEVGDGLQDQMNCMMGALQELKLLQVQTALEQLEISGGTPTFSCPESSQEQPECPRWQGSGGPAGPAAWTSSSQPSFDSSPKLPCRRSVCGKELAVLPKTQLPEEHQSCTQQGTEWVEPDDWTSTLMSRGRNRQPLVLGDNVFADLVGNWLDLPELEKGGEKGETGGSIEPKGEKGQSRELGRKFALTANIFRKFLRSVRPDRDRLLKEKPGWMTPMVSESRAGRSKKVKKRSLSKGSGRFPFSSTGEPRHIETPATSSPKALEPSCRGFDINTAVWV
Tissue specificity:Enriched in the nervous system. {ECO:0000269|PubMed:26292052}.
Induction:
Developmental stage:During development, expressed in oligodendrocyte progenitor cells and in the proliferative neuronal progenitors in the developing cerebellum. In the embryonic brain, not expressed in immature newborn neurons, except for the cells residing in the marginal zone of the embryonic telencephalon. As brain development proceeds during the postnatal stage, expressed in some populations of immature neurons, including the neocortical pyramidal neurons, hippocampal pyramidal neurons and granule cells migrating in the cerebellar cortex. In the adult brain, expression is confined in terminally differentiated neurons in the restricted forebrain regions. {ECO:0000269|PubMed:26292052}.
Protein families:INKA family