ZBT18_MOUSE Q9WUK6
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UniProt:Q9WUK6
Recommended name：Zinc finger and BTB domain-containing protein 18
EC number：
Alternative names：(58 kDa repressor protein) (Transcriptional repressor RP58) (Zinc finger protein 238) (Zfp-238)
Cleaved into：
GeneID：30928
Gene names (primary )：Zbtb18
Gene names (synonym )：Rp58 Zfp238 Znf238
Gene names (ORF )：
Length：522
Mass：58385
Sequence：MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHMAGDLPSDEDEGEDDKLNILPSKRDLAAEPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMENSLLPYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK
Tissue specificity：
Induction：
Developmental stage：In the developing brain, expression is detected at embryonic day (E) 10 in the neuroepithelium, and subsequently in the ventricular zones of the cerebral cortex in the 12 dpc embryo. Strong expression is observed in the preplate in the cerebral cortex from this stage onward. High levels of expression continue to be detected in the cortical plate and subventricular zone of the neocortex, hippocampus, and parts of the amygdala, but not in the thalamus or striatum. In the developing cerebral cortex, it is expressed both in postmitotic glutamatergic projection neurons and in their progenitor cells, but not in GABAergic interneurons. Also expressed in the adult neocortex, hippocampus, parts of the amygdala and granule cells in the cerebellum. {ECO:0000269|PubMed:19409883}.
Protein families：Krueppel C2H2-type zinc-finger protein family, ZBTB18 subfamily