H2B1A_MOUSE P70696
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UniProt:P70696
Recommended name:Histone H2B type 1-A
EC number:
Alternative names:(Histone H2B, testis) (Testis-specific histone H2B)
Cleaved into:
GeneID:319177
Gene names (primary ):H2bc1
Gene names (synonym ):Hist1h2ba Th2b
Gene names (ORF ):
Length:127
Mass:14237
Sequence:MPEVAVKGATISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
Tissue specificity:Mainly expressed in testis, and the corresponding protein is also present in mature sperm. Also present in metaphase oocytes (at protein level). {ECO:0000269|PubMed:23884607, ECO:0000269|PubMed:8672246}.
Induction:
Developmental stage:Accumulates at 10 day postpartum (dpp), when pre-leptotene/leptotene spermatocytes first appear and when H2B expression shows a drastic decrease. Replaces H2B by 18 dpp in spermatocytes. Also present in metaphase oocytes and in the female pronucleus at fertilization and is also rapidly incorporated into the male pronucleus. {ECO:0000269|PubMed:23884607}.
Protein families:Histone H2B family