Focal Adhesion
The Forkhead signaling pathway is a conserved, evolutionarily ancient molecular network centered on Forkhead box (FOX) transcription factors—a family of proteins characterized by a highly conserved "Forkhead" DNA-binding domain (≈100 amino acids) that mediates sequence-specific binding to target gene promoters. This pathway regulates a diverse array of critical biological processes across eukaryotes, from development and metabolism to stress responses and aging, with dysregulation closely linked to human diseases including cancer, metabolic disorders, and neurodegeneration.
Product List
| Target | Catalog# | Product Name | Reactivity | Application |
|---|---|---|---|---|
alpha Actinin/ACTN1 | alpha Actinin/ACTN1 Rabbit Monoclonal Antibody | Human, Mouse, Rat | WB |
Related Products
Super-sensitive ECL chemiluminescent reagent
References
- Fox transcription factors: from development to disease. Golson ML, et al. Development. 2016. [PMID: 27965437]
- roning out the details of ferroptosis. Zhang DD. Nat Cell Biol. 2024. [PMID: 38429476]
