FOXD1_MOUSE Q61345
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UniProt:Q61345
Recommended name：Forkhead box protein D1
EC number：
Alternative names：(Brain factor 2) (BF-2) (Forkhead-related protein FKHL8) (Forkhead-related transcription factor 4) (FREAC-4) (HFH-BF-2)
Cleaved into：
GeneID：15229
Gene names (primary )：Foxd1
Gene names (synonym )：Fkhl8 Freac4 Hfhbf2
Gene names (ORF )：
Length：456
Mass：45371
Sequence：MTLSTEMSDASGLAEETDIDVVGEGEDDEEEEDDDDEGGGGRGGGGSRLPSSAQRRRRSYAGEDDLEDLEEEDDDDLLLASRPAASPAPPGPAPAPGTGSGGCSGAGAGGGAGGGTGAGTGGGAKNPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISSRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLLAPHAAAEALLLRGAGPAAGAGDPGAALFPPPPPPPACGYGAYGCAYGLQLPPCAPPSALFAAAAAAAAAAFHPHSPPPPPPPPPPPPGAAAELARTAFGYRSHALAAALPGPLQAAAVKAGGPGAAALARSPFSIESLIGRTRGPAAAGAHVSSGAASGTAPGPGGGGCAVQAAAGPAVALTRSLVVAAAAAASSVSSSAALGTLHQGTALSSVENFTARISNC
Tissue specificity：Predominantly expressed in the CNS and temporal half of the retina. Also expressed in the condensed head mesenchyme, metanephric blastema of the developing kidney, cortex of the adrenal gland, condensed mesenchyme at the base of the follicles of vibrassae and cartilage perichondrium of the developing vertebrate.
Induction：
Developmental stage：At 9.5 dpc embryos, expressed in a limited region of the neuroepithelium and also in the temporal half of the primary optic cup and the optic stalk. At 10.5 dpc, seen in the hypothalamus, temporal half of the optic stalk, and temporal hemiretina. At 12.5 dpc and 13.5 dpc a high expression is seen in regions of condensed mesenchyme of the head, and as neuroepithelial cells begin to differentiate and migrate outward from the ventricular zone, expression declines markedly. By 16.5 dpc levels are diminished and restricted to unfused pockets along the exhausted ventricular zone.
Protein families：