RN112_MOUSE   Q96DY5


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UniProt:Q96DY5

Recommended name:RING finger protein 112

EC number:EC 2.3.2.27

Alternative names:(Brain finger protein) (Neurolastin) (Zinc finger protein 179)

Cleaved into:

GeneID:22671

Gene names  (primary ):Rnf112

Gene names  (synonym ):Bfp Znf179

Gene names  (ORF ):

Length:654

Mass:71275

Sequence:MPRPVLSVTAFCHRLGKRESKRSFMGNSSNSWVLPREEAQGWMGQAVQGGTRTSRSHASFPKLELGLGHRPSPTREPPTCSICLERLREPISLDCGHDFCIRCFSTHRIPGCELPCCPECRKICKQRKGLRSLGERMKLLPQRPLPPALQETCAVRAERLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHSGKSFLLDHLLSGLPSLESGDSGRPRAEGSLPGIRWGANGLTRGIWMWSHPFLLGKEGKKVAVFLVDTGDVMSPELSKETRVKLCALTMMLSSYQILNTSQELKDTDLGYLEMFVHVAEVMGKHYGMVPIQHLDLLVRDSSHHNKSGQGHVGDILQKLSGKYPKVQELLLGKRARCYLLPAPERQWVNKDQASPRGNTEDDFSHHFRAYILDVLSTAPQHAKSRCQGYWSEGRAVARGDRRLLTGQQLAQEIKNLSGWMGKTGPSFNSPDEMAAQLHDLRKVEAAKKEFEEYVRQQDIATKRIFSALRVLPDTMRNLLSTQKDAILARHGVALLCKEREQTLEALEAELQAEAKAFMDSYTMRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALAAEAGMVAAGAAVGATGAAVVGGGVGAGLAATVGCMEKEEDERVQGGDREPLLQEE

Tissue specificity:Expressed in most of the brain areas, including cortex, striatum, hippocampus, thalamus, and cerebellum (at protein level). Expressed in lateral amygdaloid nucleus, and ventromedial hypothalamus. Also expressed strongly in the marginal zone of brain vesicles, optic stalk, and cartilage primordium. {ECO:0000269|PubMed:21566658, ECO:0000269|PubMed:26951452, ECO:0000269|PubMed:9806830}.

Induction:Up-regulated by traumatic brain injury and hydrogen peroxide (at protein level). {ECO:0000269|PubMed:27918959}.

Developmental stage:

Protein families:TRAFAC class dynamin-like GTPase superfamily, GB1/RHD3 GTPase family, GB1 subfamily


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