GNAT3_MOUSE   Q3V3I2


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UniProt:Q3V3I2

Recommended name:Guanine nucleotide-binding protein G(t) subunit alpha-3

EC number:

Alternative names:(Gustducin alpha-3 chain)

Cleaved into:

GeneID:242851

Gene names  (primary ):Gnat3

Gene names  (synonym ):

Gene names  (ORF ):

Length:354

Mass:40316

Sequence:MGSGISSESKESARRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSKQECMEFKAVIYSNTLQSILAIVKAMATLGIDYVNPRSREDQEQLHSMANTLEDGDMTPQLAEIIKRLWGDPGIQACFERASEYQLNDSAAYYLNDLDRLTAPGYVPNEQDVLHSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYFATTSIVLFLNKKDLFQEKVAKVHLSICFPEYTGPNTFEDAGNYIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF

Tissue specificity:Expressed in taste buds (sensory organs of clustered epithelial cells) of the circumvallate and fungiform papillae of the tongue as well as in palatal taste buds at protein level. Expressed in enteroendocrine cells of the gut, such as in subsets of enteroendocrine cells in the midjejunum and brush cells. Detected also in spermatozoa. {ECO:0000269|PubMed:14637165, ECO:0000269|PubMed:17021831, ECO:0000269|PubMed:17229761, ECO:0000269|PubMed:17290008, ECO:0000269|PubMed:17724332}.

Induction:

Developmental stage:From week 1 to 7, the number of cells expressing GNAT3 in single taste buds increases within fungiform papilla; by week 7, the number reached the value found in adults. Expressed in cell bodies and axons of facial motor neurons at 10.5 dpc. {ECO:0000269|PubMed:14627646, ECO:0000269|PubMed:16933139}.

Protein families:G-alpha family, G(i/o/t/z) subfamily


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